Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665605 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL6657756 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL11762907 | 0.86 | MAPT (0.45) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL6552377 | 0.83 | CES1 (0.46) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL11435701 | 0.82 | MAPT (0.48) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL11435704 | 0.82 | MAPT (0.48) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL3877253 | 0.81 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL9775669 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL9775673 | 0.80 | ALDH1A1 (0.45) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 | |
| SCHEMBL11048446 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTL3MBTL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213638-A1 | Method for the asymmetric hydrogenation of olefins utilising photoisomerisation | DSM IP Assets B.V. (NL) | 2010-08-04 | — | — | EP | disclosed |
| WO-2004011414-A1 | E-ISOMERIC β-AROMATIC OR HETEROAROMATIC SUBSTITUTED β-ACYLAMINO-ACRYLATES AND METHODS OF PREPARING THE SAME | DSM IP ASSETS B.V. (NL) | 2004-02-05 | — | — | WO | disclosed |