Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.78 |
| ▸ | CASP7 | P55210 | 15/20 | 0.78 |
| ▸ | CASP1 | P29466 | 8/20 | 0.78 |
| ▸ | CASP9 | P55211 | 6/20 | 0.78 |
| ▸ | CASP4 | P49662 | 3/20 | 0.63 |
| ▸ | CASP10 | Q92851 | 3/20 | 0.63 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.63 |
| ▸ | CASP5 | P51878 | 1/20 | 0.63 |
| ▸ | CASP6 | P55212 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29362585 | 0.89 | CASP3 (0.76) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL17326941 | 0.89 | CASP3 (0.72) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL7887169 | 0.88 | CASP3 (1.00) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL29732392 | 0.88 | CASP3 (0.71) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL20239336 | 0.88 | CASP3 (0.71) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL9962302 | 0.87 | CASP3 (0.81) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL9961850 | 0.86 | CASP3 (0.85) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL30002726 | 0.86 | CASP3 (0.69) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL16770334 | 0.85 | CASP3 (0.68) | CASP3CASP7CASP1CASP9CASP4 | |
| SCHEMBL28540771 | 0.85 | CASP3 (0.68) | CASP3CASP7CASP1CASP9CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866866-B1 | MCH3, AN APOPTOTIC PROTEASE, NUCLEIC ACIDS ENCODING AND METHODS OF USE | IDUN PHARMACEUTICALS INC (US) | 2004-07-21 | — | — | EP | disclosed |