Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.44 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658294 | 1.00 | MEN1 (0.63) | MEN1KMT2ANPC1POLBKDM4E | |
| SCHEMBL6655804 | 0.82 | IDO1 (0.53) | MEN1KMT2ANPC1POLBKDM4E | |
| SCHEMBL6655810 | 0.82 | IDO1 (0.53) | MEN1KMT2ANPC1POLBKDM4E | |
| SCHEMBL13800038 | 0.79 | KDM4E (0.70) | MEN1KMT2ANPC1POLBKDM4E | |
| SCHEMBL6648945 | 0.79 | IDO1 (0.50) | MEN1KMT2ANPC1POLBKDM4E | |
| SCHEMBL6648937 | 0.79 | IDO1 (0.50) | MEN1KMT2ANPC1POLBKDM4E | |
| SCHEMBL16154384 | 0.78 | MEN1 (0.60) | MEN1KMT2ANPC1POLBKDM4E | |
| SCHEMBL6783645 | 0.77 | IDO1 (0.48) | MEN1KMT2ANPC1POLBKDM4E | |
| SCHEMBL6783653 | 0.77 | IDO1 (0.48) | MEN1KMT2ANPC1POLBKDM4E | |
| SCHEMBL18288173 | 0.77 | MEN1 (1.00) | MEN1KMT2ANPC1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412335-A4 | ENANTIOSELECTIVE TRANSFORMATION OF $g(a), $g(b)-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2004-11-17 | — | — | EP | disclosed |
| US-6784323-B2 | Enantioselective transformation of α,β-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-08-31 | — | — | US | disclosed |
| EP-1412335-A2 | ENANTIOSELECTIVE TRANSFORMATION OF $g(a), $g(b)-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2004-04-28 | — | — | EP | disclosed |
| US-20030109718-A1 | Enantioselective transformation of alpha, beta-unsaturated aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-06-12 | — | — | US | disclosed |
| WO-2003002491-A2 | ENANTIOSELECTIVE TRANSFORMATION OF α, β-UNSATURATED ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109718-A1 | Enantioselective transformation of alpha, beta-unsaturated aldehydes using chiral organic catalysts | ALDH1A1, GAR1, ALDH1B1 | MEN1 3230/4885KMT2A 794/4885NPC1 2972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.