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Sugi Predict / Targets / ALDH1B1

ALDH1B1

Aldehyde dehydrogenase X, mitochondrial · P30837 · ALDH1B1 on Sugi Atlas →

1,785 patent compounds predicted against ALDH1B1, 1,455 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL8226455 SCHEMBL8226455 0.42 5/20
SCHEMBL8229629 SCHEMBL8229629 0.46 4/20
SCHEMBL6998915 SCHEMBL6998915 0.42 3/20
SCHEMBL6995788 SCHEMBL6995788 0.40 3/20
SCHEMBL3660493 SCHEMBL3660493 0.36 3/20
SCHEMBL3767036 SCHEMBL3767036 0.61 2/20
SCHEMBL4710884 SCHEMBL4710884 0.59 2/20
SCHEMBL7532636 SCHEMBL7532636 0.59 2/20
SCHEMBL4711136 SCHEMBL4711136 0.57 2/20
SCHEMBL4710685 SCHEMBL4710685 0.55 2/20
SCHEMBL4711029 SCHEMBL4711029 0.54 2/20
SCHEMBL4790015 SCHEMBL4790015 0.53 2/20
SCHEMBL4708695 SCHEMBL4708695 0.52 2/20
SCHEMBL4710620 SCHEMBL4710620 0.52 2/20
SCHEMBL4714180 SCHEMBL4714180 0.52 2/20
SCHEMBL4711181 SCHEMBL4711181 0.52 2/20
SCHEMBL4712732 SCHEMBL4712732 0.52 2/20
SCHEMBL4759826 SCHEMBL4759826 0.52 2/20
SCHEMBL4789332 SCHEMBL4789332 0.52 2/20
SCHEMBL4709482 SCHEMBL4709482 0.52 2/20

Clinical trials — most relevant to ALDH1B1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Semaglutide and Vascular Regeneration PHASE4UNKNOWN
Carboplatin and Eribulin Mesylate in Triple Negative Breast Cancer Patients PHASE2UNKNOWN
Disulfiram and Cisplatin in Refractory TGCTs. PHASE2COMPLETED
ALDH2 Genetic Testing in East Asian Community nanNOT_YET_RECRUITING
ADH1B and ALDH Gene Variants and Lung Cancer Risk nanNOT_YET_RECRUITING
Functional Investigation of Endothelial Function and Regenerative Cell Exhaustion nanNOT_YET_RECRUITING
ALDH2 Single Nucleotide Polymorphisms and Prognosis of Esophageal Cancer Patients nanRECRUITING
Environmental and Biological Monitoring Pilot Study for Polycyclic Aromatic Hydrocarbons in Linxian, China nanCOMPLETED
Determination of ALDH1b1 and ALDH2 Polymorphisms Frequency in the Brazilian Population nanUNKNOWN
Bipolar Disorder With Alcoholism in Han Chinese nanUNKNOWN
Alcohol Metabolism and Disease Risk in Asians nanCOMPLETED
Relationship Between ALDH2 and CIN nanUNKNOWN
Identifying Genes That May Increase the Risk for Heart Disease in African Americans nanCOMPLETED
Gene-by-Smoking Interactions and Risk of Atherosclerosis - Ancillary to ARIC nanCOMPLETED
Genetic and Environmental Risk Factors Related to Esophageal Cancer nanACTIVE_NOT_RECRUITING
ALDH1A1 Expression in Invasive Mammary Carcinoma nanUNKNOWN
High Risk Breast Clinic: Protocol for Women at Increased Risk for Developing Breast Cancer nanRECRUITING
The Genetic Basis for Vulnerability to Substance Abuse nanCOMPLETED
Common Variants in Candidate Genes and Premature MI Risk nanCOMPLETED
Peking University & University of Michigan Study of MI and Atherosclerosis nanCOMPLETED
Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle nanCOMPLETED
Evaluating the Safety and Pharmacokinetics of Raltegravir in Infants nanCOMPLETED
Adrenoleukodystrophy National Registry Study nanRECRUITING
Genetic Polymorphisms in UGT1A6 and UGT2B7 in Asian Population: Association With Lung Cancer Phenotype nanUNKNOWN
Molecular Epidemiology of Parkinson's Disease nanCOMPLETED
Study of Protein Translocation in Patients With Beta-Oxidation Disorders nanCOMPLETED
Respiratory Cathepsins, Proteases Inhibitors and Glycosaminoglycans (GAG) in Mucopolysaccharidosis nanCOMPLETED
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus nanACTIVE_NOT_RECRUITING
Genetic Markers of CHD Risk in Men and Women nanCOMPLETED
Impact Of Choline in Patients With NAFLD nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a ALDH1B1 binder may also engage these)

ProteinNameSimilarity
Q9CZS1 — 1.000 Q9CZS1 →
Q5R6B5 — 1.000 Q5R6B5 →
Q2XQV4 — 1.000 Q2XQV4 →
P81178 — 1.000 P81178 →
P51977 — 1.000 P51977 →
P48644 — 1.000 P48644 →
ALDH1A1 Aldehyde dehydrogenase 1A1 1.000 landscape →
ALDH1A3 Retinaldehyde dehydrogenase 3 1.000 landscape →
Q8HYE4 — 1.000 Q8HYE4 →
Q9SU63 — 1.000 Q9SU63 →
Q9JHW9 — 1.000 Q9JHW9 →
Q25417 — 1.000 Q25417 →
P11884 — 0.998 P11884 →
P15437 — 0.998 P15437 →
Q66HF8 — 0.998 Q66HF8 →
P47738 — 0.998 P47738 →
P13601 — 0.997 P13601 →
Q5RF00 — 0.997 Q5RF00 →
Q19A30 — 0.997 Q19A30 →
Q8K4D8 — 0.997 Q8K4D8 →
Q29490 — 0.996 Q29490 →
P56533 — 0.996 P56533 →
Q28399 — 0.996 Q28399 →
O35945 — 0.996 O35945 →
P52476 — 0.996 P52476 →
P46367 — 0.996 P46367 →
Q9SAK4 — 0.996 Q9SAK4 →
P24549 — 0.996 P24549 →
Q62148 — 0.996 Q62148 →
Q84LK3 — 0.996 Q84LK3 →