SCHEMBL6658424

SCHEMBL6658424

COC(=O)[C@H](CC(=O)c1ccccc1)NC(=O)OC(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.56
KLK5 Q9Y337 2/20 0.54
JAK3 P52333 1/20 0.53
BTK Q06187 1/20 0.53
PPARA Q07869 6/20 0.51
PPARG P37231 5/20 0.51
PPARD Q03181 2/20 0.51
CTSS P25774 4/20 0.49
CTSK P43235 4/20 0.49
CTSL P07711 1/20 0.48
CTSB P07858 1/20 0.48
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
ACE P12821 1/20 0.46
CACNA1B Q00975 1/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28905329 0.89 PPARA (0.59) KMT2AJAK3BTKPPARAPPARG
SCHEMBL4802016 0.89 PPARA (0.59) KMT2AJAK3BTKPPARAPPARG
SCHEMBL3884513 0.89 PPARA (0.59) KMT2AJAK3BTKPPARAPPARG
SCHEMBL30543584 0.87 KLK5 (0.50) KMT2AKLK5JAK3BTKPPARA
SCHEMBL20117226 0.87 JAK3 (0.53) KMT2AKLK5JAK3BTKPPARA
SCHEMBL13866876 0.86 REN (0.48) KMT2AKLK5JAK3BTKPPARA
SCHEMBL3881492 0.86 REN (0.48) KMT2AKLK5JAK3BTKPPARA
SCHEMBL29750260 0.85 CTSS (0.55) CTSSCTSKCTSLCTSB
SCHEMBL2344991 0.84 KLK5 (0.57) KLK5PPARAPPARGPPARDCTSS
SCHEMBL2344987 0.84 KLK5 (0.57) KLK5PPARAPPARGPPARDCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114950558-B Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing hydrocarbon molecule benzyl site selective oxidation by using same 陕西师范大学 2023-08-11 CN disclosed
CN-114950558-A Bipiperidine skeleton tetradentate nitrogen-containing manganese catalyst and method for catalyzing benzyl-site selective oxidation of hydrocarbon molecules by using same 陕西师范大学 2022-08-30 CN disclosed
EP-1355978-B1 SURFACE-FUNCTIONALISED CARRIER MATERIAL, METHOD FOR THE PRODUCTION THEREOF AND SOLID PHASE SYNTHESIS METHOD POLY AN GES ZUR HERSTELLUNG VO (DE) 2004-08-04 EP disclosed