SCHEMBL6658545

SCHEMBL6658545

CCCCCCC1(CCCCCC)c2cc(C=O)ccc2-c2ccc(C=O)cc21

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 5/20 0.36
MMP9 P14780 5/20 0.36
MMP8 P22894 4/20 0.36
MMP13 P45452 4/20 0.36
ALDH1A3 P47895 4/20 0.35
ALDH3A1 P30838 4/20 0.35
ALDH1A1 P00352 4/20 0.35
HIF1A Q16665 1/20 0.33
EPAS1 Q99814 1/20 0.33
APP P05067 1/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.32
MMP3 P08254 1/20 0.31
PLA2G4A P47712 1/20 0.31
GPR84 Q9NQS5 1/20 0.31
FDPS P14324 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL851336 1.00 MMP2 (0.36) MMP2MMP9MMP8MMP13ALDH1A3
SCHEMBL9101904 1.00 MMP2 (0.36) MMP2MMP9MMP8MMP13ALDH1A3
SCHEMBL18894239 1.00 MMP2 (0.36) MMP2MMP9MMP8MMP13ALDH1A3
SCHEMBL30435044 1.00 MMP2 (0.36) MMP2MMP9MMP8MMP13ALDH1A3
SCHEMBL26109311 0.97 MMP2 (0.35) MMP2MMP9MMP8MMP13ALDH1A3
SCHEMBL28058189 0.94 ALDH1A1 (0.36) ALDH1A3ALDH3A1ALDH1A1TSHRFDPS
SCHEMBL14750205 0.93 MMP2 (0.38) MMP2MMP9MMP8MMP13CNR1
SCHEMBL1356093 0.93 MMP2 (0.38) MMP2MMP9MMP8MMP13CNR1
SCHEMBL2601875 0.93 MMP2 (0.38) MMP2MMP9MMP8MMP13CNR1
SCHEMBL14750260 0.93 MMP2 (0.38) MMP2MMP9MMP8MMP13CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3380541-B1 DEGRADABLE CONJUGATED POLYMERS UNIV LELAND STANFORD JUNIOR (US) 2020-04-29 EP disclosed
WO-2004003044-A2 DYNAMERS: POLYMERIC MATERIALS EXHIBITING REVERSIBLE FORMATION AND COMPONENT EXCHANGE LEHN JEAN-MARIE (FR) 2004-01-08 WO disclosed
US-6590125-B2 Electron injection and transport ability ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2003-07-08 US disclosed
US-6495273-B1 EXCELLENT IN THE ABILITY OF ELECTRON INJECTION AND TRANSPORTATION; REACTION OF FLUORINATED TETRAPHENYL DI-DIALKOXYPHOSPHINE OR DIPHOSPHONIUM DERIVATIVES WITH AROMATIC DIALDEHYDES ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE 2002-12-17 US disclosed
US-20010021464-A1 Blue light-emitting polymer prepared using a fluorinated tetraphenyl monomer and an EL device manufactured using the polymer UNILOC 2017 LLC 2001-09-13 US disclosed