Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6658630 | 0.95 | KMT2A (0.38) | TSHRALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL6656378 | 0.90 | NR4A2 (0.41) | TSHRALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL6656373 | 0.88 | ALDH1A1 (0.38) | TSHRALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL6555991 | 0.85 | PRSS1 (0.36) | TSHRALDH1A1MAPTLMNA | |
| SCHEMBL7054284 | 0.84 | CES2 (0.47) | TSHRLMNA | |
| SCHEMBL7058952 | 0.83 | CES2 (0.42) | ALDH1A1SMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL6555999 | 0.81 | TDP1 (0.33) | TSHRALDH1A1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL7056823 | 0.79 | ELANE (0.42) | TSHRSMN1; SMN2MAPTLMNA | |
| SCHEMBL7056407 | 0.77 | ALDH1A1 (0.39) | TSHRALDH1A1SMN1; SMN2MAPK1NPC1 | |
| SCHEMBL6555628 | 0.77 | TSHR (0.33) | TSHRALDH1A1SMN1; SMN2MAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005302-A1 | PROCESS FOR THE PREPARATION OF ACYLOXYSILANES | SIGMA COATINGS B.V. (NL) | 2004-01-15 | — | — | WO | disclosed |