Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681795 | 0.90 | KMT2A (0.37) | FAAH | |
| SCHEMBL6656980 | 0.82 | GRIN1 (0.34) | TSHRFAAHGRIN1GRIN2AGRIN2B | |
| SCHEMBL6656879 | 0.76 | PTPN11 (0.44) | TSHRSMPD1CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL6657967 | 0.76 | PTPN11 (0.44) | TSHRSMPD1CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL6676834 | 0.73 | KMT2A (0.35) | FAAH | |
| SCHEMBL6661830 | 0.72 | PTPN11 (0.43) | TSHRSMPD1CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL6659337 | 0.72 | PTGS2 (0.41) | TSHRFAAHSMPD1CYP1A2CYP19A1 | |
| SCHEMBL6655589 | 0.68 | PTPN11 (0.38) | TSHRFAAHPTPN11 | |
| SCHEMBL6656108 | 0.67 | PTPN11 (0.43) | FAAHPTPN11 | |
| SCHEMBL6659332 | 0.67 | PTPN11 (0.41) | TSHRPTPN11PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1160233-B1 | Novel terphenyl compounds | SHARP KK (JP) | 2004-07-21 | — | — | EP | claimed |
| EP-1160233-A2 | Novel terphenyl compounds | SHARP KABUSHIKI KAISHA (JP) | 2001-12-05 | — | — | EP | claimed |
| EP-1160233-B1 | Novel terphenyl compounds | SHARP KK (JP) | 2004-07-21 | — | — | EP | disclosed |
| EP-1160233-A2 | Novel terphenyl compounds | SHARP KABUSHIKI KAISHA (JP) | 2001-12-05 | — | — | EP | disclosed |