Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | OGG1 | O15527 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31186169 | 0.87 | PDPK1 (0.70) | PDPK1CES2CES1CA1CA2 | |
| SCHEMBL28636492 | 0.84 | CES2 (0.52) | PDPK1CES2CES1CA1CA2 | |
| SCHEMBL10361494 | 0.82 | CES2 (0.50) | PDPK1CES2CES1CA1CA2 | |
| SCHEMBL11755739 | 0.80 | CES2 (0.48) | PDPK1CES2CES1CA1CA2 | |
| SCHEMBL7734235 | 0.78 | CES2 (0.56) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL6851984 | 0.78 | PDPK1 (0.59) | PDPK1CES2CES1CA1CA2 | |
| SCHEMBL27685854 | 0.78 | PDPK1 (0.87) | PDPK1CES2CA1CA2LMNA | |
| SCHEMBL2096724 | 0.78 | GSK3B (0.64) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL29003581 | 0.78 | CES2 (0.56) | CES2CES1CA1CA2GSK3B | |
| SCHEMBL7768899 | 0.76 | PDPK1 (0.57) | PDPK1CES2CES1GSK3BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1282595-B1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-07-14 | — | — | EP | disclosed |
| US-6683211-B1 | FUNGICIDES FOR CROPS | SYNGENTA CROP PROTECTION, INC. | 2004-01-27 | — | — | US | disclosed |
| EP-1282595-A1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | Syngenta Participations AG (CH) | 2003-02-12 | — | — | EP | disclosed |
| WO-2001087822-A1 | NOVEL PHENYL-PROPARGYLETHER DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-11-22 | — | — | WO | disclosed |
| US-5869683-A | Processes for producing 1-substituted-2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0705823-A1 | Process for producing 1-substituted-2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1996-04-10 | — | — | EP | disclosed |