Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | CES1 | P23141 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL28958779 | 0.98 | PDPK1 (0.55) | PDPK1ALDH1A1CES2CES1LMNA | |
| SCHEMBL31186169 | 0.87 | PDPK1 (0.70) | PDPK1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL10384383 | 0.84 | ALDH1A1 (0.52) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL8388071 | 0.82 | ALDH1A1 (0.50) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL14369396 | 0.81 | PDPK1 (0.57) | PDPK1ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL11749506 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL11599419 | 0.80 | SMN1; SMN2 (0.48) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL2233657 | 0.80 | ALDH1A1 (0.59) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL7457651 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1CES2CES1LMNASMN1; SMN2 | |
| SCHEMBL585256 | 0.78 | ALDH1A1 (0.56) | ALDH1A1CES2CES1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115724727-A | Method for preparing cyazofamid intermediate 2,2-dichloro-4' -methylacetophenone | 河北工业职业技术学院 | 2023-03-03 | — | — | CN | claimed |
| CN-214106913-U | Preparation facilities is used with mediation to methyl dichloroacetophenone | 如东众意化工有限公司 | 2021-09-03 | — | — | CN | claimed |
| CN-109400534-B | Production process of 1-hydroxy-4- (4' -methylphenyl) -2-methoxy oxime imidazole-3-oxide | 兰博尔开封科技有限公司 | 2020-11-03 | — | — | CN | claimed |
| CN-110963907-B | Green synthesis of 2, 2-dialkoxy acetophenone derivative | 中国农业科学院植物保护研究所 | 2023-12-19 | — | — | CN | disclosed |
| CN-112961043-B | Solvent-free preparation of alpha, alpha-dichloroketone | 重庆医科大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-115724727-A | Method for preparing cyazofamid intermediate 2,2-dichloro-4' -methylacetophenone | 河北工业职业技术学院 | 2023-03-03 | — | — | CN | disclosed |
| CN-115724727-A | Method for preparing cyazofamid intermediate 2,2-dichloro-4' -methylacetophenone | 河北工业职业技术学院 | 2023-03-03 | — | — | CN | disclosed |
| CN-115724727-A | Method for preparing cyazofamid intermediate 2,2-dichloro-4' -methylacetophenone | 河北工业职业技术学院 | 2023-03-03 | — | — | CN | disclosed |
| CN-214106913-U | Preparation facilities is used with mediation to methyl dichloroacetophenone | 如东众意化工有限公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-214106913-U | Preparation facilities is used with mediation to methyl dichloroacetophenone | 如东众意化工有限公司 | 2021-09-03 | — | — | CN | disclosed |
| CN-112961043-A | Preparation of alpha, alpha-dichloroketone under solvent-free condition | 重庆医科大学 | 2021-06-15 | — | — | CN | disclosed |
| US-9464038-B2 | Method for producing specific oximes and oximethers | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-10-11 | — | — | US | disclosed |
| US-20160107986-A1 | IMPROVED METHOD FOR PRODUCING SPECIFIC OXIMES AND OXIMETHERS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
| CN-102424671-B | Synthesis method of 4-chloro-2-cyano-1-dimethylamino-sulfonyl-5-(4-methylphenyl)imidazo | XIAN MODERN CHEMISTRY RES INST | 2014-05-14 | — | — | CN | disclosed |
| CN-102424671-A | Synthesis method of 4-chloro-2-cyano-1-dimethylaminosulfonyl-5- (4-methylphenyl) imidazole | XIAN MODERN CHEMISTRY RES INST | 2012-04-25 | — | — | CN | disclosed |
| JP-2001048825-A | PRODUCTION OF HALOGENATED ACETOPHENONE | ISHIHARA SANGYO KAISHA LTD | 2001-02-20 | — | — | JP | disclosed |
| WO-2000075094-A2 | METHOD FOR PRODUCING A HALOGENATED ACETOPHENONE | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-12-14 | — | — | WO | disclosed |
| US-5869683-A | Processes for producing 1-substituted-2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0705823-A1 | Process for producing 1-substituted-2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1996-04-10 | — | — | EP | disclosed |
| EP-0089650-A1 | Process for producing antifungal pyridazinone derivatives and certain novel compounds produced by such a process | SANKYO COMPANY LIMITED (JP) | 1983-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160107986-A1 | IMPROVED METHOD FOR PRODUCING SPECIFIC OXIMES AND OXIMETHERS | HAO2, OXER1, OXSR1 | PDPK1 4225/4885ALDH1A1 1247/4885CES2 1477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.