Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27638550 | 0.83 | HSD11B1 (0.56) | RECQLMEN1KMT2ANPC1HSD11B1 | |
| SCHEMBL6660239 | 0.81 | RECQL (0.53) | RECQLMEN1KMT2ANPC1HSD11B1 | |
| SCHEMBL1699941 | 0.79 | RECQL (0.58) | RECQLMEN1KMT2ANPC1HSD11B1 | |
| SCHEMBL6660055 | 0.77 | RECQL (0.49) | RECQLMEN1KMT2ANPC1HSD11B1 | |
| SCHEMBL8761020 | 0.77 | RECQL (0.56) | RECQLMEN1KMT2ANPC1HSD11B1 | |
| SCHEMBL4750334 | 0.76 | RECQL (0.47) | RECQLMEN1KMT2ANPC1HSD11B1 | |
| SCHEMBL6664422 | 0.76 | KMT2A (0.52) | RECQLMEN1KMT2AHSD11B1MAPT | |
| Acetic Acid SCHEMBL28778736 | 0.76 | RECQL (0.54) | RECQLMEN1KMT2ANPC1HSD11B1 | |
| SCHEMBL1516246 | 0.74 | MAPK1 (0.58) | RECQLMEN1KMT2ANPC1HSD11B1 | |
| SCHEMBL28052900 | 0.73 | LMNA (0.60) | MEN1KMT2ANPC1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1447397-A1 | Polyfunctional sulfonamides and sulfonates and process for preparing them | Ecole Polytechnique Fédérale de Lausanne (CH) | 2004-08-18 | — | — | EP | claimed |
| EP-1447397-A1 | Polyfunctional sulfonamides and sulfonates and process for preparing them | Ecole Polytechnique Fédérale de Lausanne (CH) | 2004-08-18 | — | — | EP | disclosed |