Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 4/20 | 0.32 |
| ▸ | NOS1 | P29475 | 4/20 | 0.32 |
| ▸ | NOS2 | P35228 | 4/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215701 | 1.00 | TLR4 (0.51) | TLR4CYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL1666553 | 1.00 | TLR4 (0.51) | TLR4CYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL9979138 | 0.90 | TLR4 (0.51) | TLR4CYP2C9OPRM1OPRL1NOS3 | |
| SCHEMBL7912298 | 0.90 | TLR4 (0.44) | TLR4CYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL7912304 | 0.90 | TLR4 (0.44) | TLR4CYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL7912286 | 0.90 | TLR4 (0.44) | TLR4CYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL6454016 | 0.89 | TLR4 (0.50) | TLR4CYP2C9OPRM1OPRL1 | |
| SCHEMBL6451893 | 0.89 | TLR4 (0.50) | TLR4CYP2C9OPRM1OPRL1 | |
| SCHEMBL6451888 | 0.89 | TLR4 (0.50) | TLR4CYP2C9OPRM1OPRL1 | |
| SCHEMBL6752745 | 0.88 | CYP1A2 (0.47) | TLR4MAPTLMNANOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117550951-A | Preparation method of 1- [4- (4- (4-propylcyclohexyl)) -1-alkene-cyclohexyl ] -4-trifluoromethyl benzene | 江苏广域化学有限公司 | 2024-02-13 | — | — | CN | claimed |
| US-12618008-B2 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2026-05-05 | — | — | US | disclosed |
| US-12595417-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2026-04-07 | — | — | US | disclosed |
| US-20250361444-A1 | Liquid Crystal Medium | MERCK PATENT GMBH (DE) | 2025-11-27 | — | — | US | disclosed |
| EP-4653511-A1 | LIQUID CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2025-11-26 | — | — | EP | disclosed |
| US-20250215323-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2025-07-03 | — | — | US | disclosed |
| EP-4578929-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2025-07-02 | — | — | EP | disclosed |
| CN-119120038-A | Liquid crystal medium, liquid crystal display device containing same and compound | 默克专利股份有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-114144498-B | Liquid crystal medium, liquid crystal display device containing same and compound | 默克专利股份有限公司 | 2024-09-10 | — | — | CN | disclosed |
| EP-3994234-B1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | MERCK PATENT GMBH (DE) | 2024-02-21 | — | — | EP | disclosed |
| US-4477369-A | New high temperature liquid-crystalline substances consisting of 4 or 5 six-member-rings and liquid-crystalline compositions containing same | CHISSO CORPORATION (JP) | 1984-10-16 | — | — | US | disclosed |
| EP-0062470-B1 | LIQUID CRYSTAL BENZENE DERIVATIVES | Chisso Corporation (JP) | 1984-08-15 | — | — | EP | disclosed |
| US-4439340-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1984-03-27 | — | — | US | disclosed |
| EP-0096850-A1 | Trans-4-alkyloxymethyl-1-(4'-substituted biphenylyl-4)cyclohexanes and liquid crystal compositions containing the same | Chisso Corporation (JP) | 1983-12-28 | — | — | EP | disclosed |
| US-4422951-A | Liquid crystal benzene derivatives | CHISSO CORPORATION (JP) | 1983-12-27 | — | — | US | disclosed |
| EP-0094487-A1 | Hydroterphenyls, their preparation and their use in dielectric liquid crystal material | MERCK PATENT GmbH (DE) | 1983-11-23 | — | — | EP | disclosed |
| EP-0090671-A1 | Carbocylic esters having liquid-crystal properties at high temperatures | Chisso Corporation (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4405488-A | LOW VISCOSITY, HIGH TRANSPARENT POINT | CHISSO CORPORATION (JP) | 1983-09-20 | — | — | US | disclosed |
| EP-0084974-A1 | Carbocyclic compounds with liquid-crystal properties | Chisso Corporation (JP) | 1983-08-03 | — | — | EP | disclosed |
| EP-0062470-A1 | Liquid crystal benzene derivatives | Chisso Corporation (JP) | 1982-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595417-B2 | Liquid-crystal medium | MEF2D, HCN2, HCN3 | TLR4 3498/4885CYP2C9 3080/4885ALDH1A1 1628/4885 |
| US-20250361444-A1 | Liquid Crystal Medium | FES, SOST, VIM | TLR4 1413/4885CYP2C9 4579/4885ALDH1A1 4846/4885 |
| US-12618008-B2 | Liquid crystal medium | VIM, FES, NES | TLR4 1626/4885CYP2C9 4497/4885ALDH1A1 4461/4885 |
| US-20250215323-A1 | LIQUID-CRYSTAL MEDIUM | NEFM, FES, FLNB | TLR4 4406/4885CYP2C9 4071/4885ALDH1A1 3464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.