Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.34 |
| ▸ | NOS3 | P29474 | 4/20 | 0.32 |
| ▸ | NOS1 | P29475 | 4/20 | 0.32 |
| ▸ | NOS2 | P35228 | 4/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1666552 | 1.00 | TLR4 (0.51) | TLR4CYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL1666553 | 1.00 | TLR4 (0.51) | TLR4CYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL9979138 | 0.90 | TLR4 (0.51) | TLR4CYP2C9OPRM1OPRL1NOS3 | |
| SCHEMBL7912298 | 0.90 | TLR4 (0.44) | TLR4CYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL7912304 | 0.90 | TLR4 (0.44) | TLR4CYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL7912286 | 0.90 | TLR4 (0.44) | TLR4CYP2C9ALDH1A1MAPTLMNA | |
| SCHEMBL6454016 | 0.89 | TLR4 (0.50) | TLR4CYP2C9OPRM1OPRL1 | |
| SCHEMBL6451893 | 0.89 | TLR4 (0.50) | TLR4CYP2C9OPRM1OPRL1 | |
| SCHEMBL6451888 | 0.89 | TLR4 (0.50) | TLR4CYP2C9OPRM1OPRL1 | |
| SCHEMBL6752745 | 0.88 | CYP1A2 (0.47) | TLR4MAPTLMNANOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030545-A | HAVING A REDUCED VISCOSITY, A WIDE LIQUID CRYSTAL TEMPERATURE RANGE (HIGH CLEARING POINT), A HIGH CHEMICAL STABILITY (EXTREMELY HIGH SPECIFIC RESISTANCE, HIGH VOLTAGE HOLDING RATIO) AND A HIGH SOLUBILITY WITH OTHER LIQUID-CRYSTAL | CHISSO CORPORATION (JP) | 2000-02-29 | — | — | US | disclosed |