Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2BTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3MPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PPARGSLC6A2SLC6A3SLC6A4SMOTYK2pol
The experimentally established mechanism targets of Benzylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylamine SCHEMBL8533927 | 1.00 | LOXL2 (0.64) | LOXL2CYP2D6CYP2C19CYP1A2CYP2C9 | |
| Benzylamine SCHEMBL10445229 | 1.00 | LOXL2 (0.64) | LOXL2CYP2D6CYP2C19CYP1A2CYP2C9 | |
| Benzylamine SCHEMBL2800847 | 0.91 | LOXL2 (0.58) | LOXL2CYP2D6CYP2C19CYP1A2CYP2C9 | |
| Benzylamine SCHEMBL2800850 | 0.91 | LOXL2 (0.58) | LOXL2CYP2D6CYP2C19CYP1A2CYP2C9 | |
| Benzylamine SCHEMBL2841170 | 0.85 | LOXL2 (0.78) | LOXL2CYP2D6CYP2C19CYP1A2CYP2C9 | |
| Benzylamine SCHEMBL2841167 | 0.85 | LOXL2 (0.78) | LOXL2CYP2D6CYP2C19CYP1A2CYP2C9 | |
| Benzylamine SCHEMBL11588019 | 0.84 | LOXL2 (0.61) | LOXL2CYP2D6CYP2C19CYP1A2CYP2C9 | |
| Benzylamine SCHEMBL25352130 | 0.83 | LOXL2 (0.74) | LOXL2CYP2D6CYP2C19CYP1A2CYP2C9 | |
| Benzylamine SCHEMBL3188490 | 0.83 | LOXL2 (0.74) | LOXL2CYP2D6CYP2C19CYP1A2CYP2C9 | |
| Benzylamine SCHEMBL3891720 | 0.83 | LOXL2 (0.74) | LOXL2CYP2D6CYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115714235-A | Separator and battery including the same | 武汉微美新材料科技有限公司 | 2023-02-24 | — | — | CN | disclosed |
| CN-115347324-A | Ceramic coating, and diaphragm and lithium ion battery comprising same | 武汉微美新材料科技有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-114975939-A | Water-based cathode slurry, cathode pole piece and lithium ion battery | 武汉微美新材料科技有限公司 | 2022-08-30 | — | — | CN | disclosed |
| EP-0859757-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | Farmak A.S. (CZ) | 1998-08-26 | — | — | EP | disclosed |
| WO-1997017325-A1 | DERIVATES OF N,N-DIMETHYL-2-(ARYLTHIO)BENZYLAMINE, THEIR SALTS, METHODS OF PREPARATION AND THEIR USE IN PHARMACEUTICAL MEDICAMENTS | FARMAK A.S. (CZ) | 1997-05-15 | — | — | WO | disclosed |
| CN-1042910-A | The allylamine derivatives that replaces, their production method and application thereof | BANYU PHARMA CO LTD (JP) | 1990-06-13 | — | — | CN | disclosed |