SCHEMBL6660893

SCHEMBL6660893

CCC[SiH](O)CC(O)C=O

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.37
GAPDH P04406 2/20 0.31
TRPA1 O75762 1/20 0.31
DDAH1 O94760 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1828098 0.69
SCHEMBL1827792 0.66
SCHEMBL16845288 0.66
SCHEMBL196889 0.66
SCHEMBL28628309 0.65 AKR1B1 (0.42) AKR1B1GAPDHTRPA1DDAH1MAPT
SCHEMBL9893247 0.65
SCHEMBL10200365 0.65
SCHEMBL60321 0.65
SCHEMBL28147680 0.64
SCHEMBL27300910 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1256380-B1 Adsorbents for blood perfusion and their preparation method THIES KARSTEN DR (DE) 2004-08-25 EP claimed
WO-2002089975-A1 ADSORBENTS FOR THE PERFUSION OF BLOOD AND CORRESPONDING PRODUCTION METHOD THIES KARSTEN (DE) 2002-11-14 WO claimed
EP-1256380-A1 Adsorbents for blood perfusion and their preparation method Thies, Karsten, Dr. (DE) 2002-11-13 EP claimed
EP-1256380-B1 Adsorbents for blood perfusion and their preparation method THIES KARSTEN DR (DE) 2004-08-25 EP disclosed
WO-2002089975-A1 ADSORBENTS FOR THE PERFUSION OF BLOOD AND CORRESPONDING PRODUCTION METHOD THIES KARSTEN (DE) 2002-11-14 WO disclosed
EP-1256380-A1 Adsorbents for blood perfusion and their preparation method Thies, Karsten, Dr. (DE) 2002-11-13 EP disclosed