⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10200365 | 1.00 | — | — | |
| SCHEMBL60321 | 1.00 | — | — | |
| Water SCHEMBL28284158 | 0.94 | — | — | |
| Acetaldehyde SCHEMBL18398681 | 0.94 | — | — | |
| SCHEMBL20838462 | 0.91 | GAPDH (0.48) | — | |
| SCHEMBL27954974 | 0.84 | AKR1B1 (0.52) | — | |
| SCHEMBL8612011 | 0.78 | TSHR (0.44) | — | |
| SCHEMBL17984935 | 0.77 | — | — | |
| SCHEMBL13900283 | 0.77 | — | — | |
| SCHEMBL8612006 | 0.76 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382590-A1 | ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USING SAME | AGAIN BIO APS (DK) | 2025-12-18 | — | — | US | disclosed |
| US-12371673-B2 | Aldehyde dehydrogenase variants and methods of using same | GENOMATICA, INC. (US) | 2025-07-29 | — | — | US | disclosed |
| US-20230416698-A1 | ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USING SAME | AGAIN BIO APS (DK) | 2023-12-28 | — | — | US | disclosed |
| US-11634692-B2 | Aldehyde dehydrogenase variants and methods of using same | GENOMATICA, INC. (US) | 2023-04-25 | — | — | US | disclosed |
| US-20220325254-A1 | ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USE | AGAIN BIO APS (DK) | 2022-10-13 | — | — | US | disclosed |
| US-11299716-B2 | Aldehyde dehydrogenase variants and methods of use | GENOMATICA, INC. (US) | 2022-04-12 | — | — | US | disclosed |
| US-20210348134-A1 | ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USING SAME | GENOMATICA, INC. (US) | 2021-11-11 | — | — | US | disclosed |
| EP-3856896-A1 | ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USING SAME | Genomatica, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |
| CN-113179645-A | Aldehyde dehydrogenase variants and methods of use thereof | 基因组股份公司 | 2021-07-27 | — | — | CN | disclosed |
| WO-2020068900-A1 | ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USING SAME | GENOMATICA, INC. (US) | 2020-04-02 | — | — | WO | disclosed |
| US-20200040312-A1 | ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USE | AGAIN BIO APS (DK) | 2020-02-06 | — | — | US | disclosed |
| EP-3601546-A1 | ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USE | Genomatica, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018183664-A1 | ALDEHYDE DEHYDROGENASE VARIANTS AND METHODS OF USE | GENOMATICA, INC. (US) | 2018-10-04 | — | — | WO | disclosed |
| US-20120151635-A1 | METHODS OF AFFECTING NITROGEN ASSIMILATION IN PLANTS | NEW YORK UNIVERSITY | 2012-06-14 | — | — | US | disclosed |
| US-7569577-B2 | Quinazoline derivatives as tyrosine kinase inhibitors | ASTRAZENECA AB (SE) | 2009-08-04 | — | — | US | disclosed |
| US-20070043009-A1 | Quinazoline derivatives as tyrosine kinase inhibitors | ASTRAZENECA AB (SE) | 2007-02-22 | — | — | US | disclosed |