SCHEMBL6660908

SCHEMBL6660908

CCC[C@H](NC(c1ccccc1)c1ccccc1)P(=O)(O)O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 7/20 0.44
SRC P12931 1/20 0.43
AOC3 Q16853 2/20 0.41
ANPEP P15144 1/20 0.41
POLB P06746 1/20 0.40
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6660913 1.00 ACP3 (0.44) ACP3SRCAOC3ANPEPPOLB
SCHEMBL6658782 0.89 NPSR1 (0.43) ACP3POLBGRIN2DGRIN3BGRIN1
SCHEMBL6658790 0.89 NPSR1 (0.43) ACP3POLBGRIN2DGRIN3BGRIN1
SCHEMBL6665628 0.88 FDPS (0.44) NPSR1
SCHEMBL6665624 0.88 FDPS (0.44) NPSR1
SCHEMBL6662872 0.87 ACP3 (0.46) ACP3SRCANPEPPOLBGRIN2D
SCHEMBL8050570 0.87 ACP3 (0.46) ACP3SRCANPEPPOLBGRIN2D
SCHEMBL30213304 0.84 POLB (0.47) AOC3POLBNPSR1
SCHEMBL6662510 0.84 POLB (0.47) POLBNPSR1
SCHEMBL6661782 0.81 GAA (0.43) AOC3POLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0877028-B1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS HOKKO CHEM IND CO (JP) 2004-08-25 EP disclosed
US-6084123-A REACTING AN IMINE WITH A PHOSPHONIC ACID ESTER USING AN ASYMMETRIC CATALYST OF A RARE EARTH METAL/ALKALI METAL-BINAPHTHOL COMPLEX; HYDROGENATION AND ACIDOLYSIS HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2000-07-04 US disclosed
EP-0877028-A1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) 1998-11-11 EP disclosed