SCHEMBL6662872

SCHEMBL6662872

CC[C@H](NC(c1ccccc1)c1ccccc1)P(=O)(O)O

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 10/20 0.46
SRC P12931 1/20 0.46
ANPEP P15144 1/20 0.43
LMNA P02545 2/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41
GRIN1 Q05586 1/20 0.41
GRIN2A Q12879 1/20 0.41
GRIN2B Q13224 1/20 0.41
GRIN2C Q14957 1/20 0.41
GRIN3A Q8TCU5 1/20 0.41
POLB P06746 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8050570 1.00 ACP3 (0.46) ACP3SRCANPEPLMNAGRIN2D
SCHEMBL6660913 0.87 ACP3 (0.44) ACP3SRCANPEPGRIN2DGRIN3B
SCHEMBL6660908 0.87 ACP3 (0.44) ACP3SRCANPEPGRIN2DGRIN3B
SCHEMBL8038647 0.83 ACP3 (0.47) ACP3SRCANPEPLMNAGRIN2D
SCHEMBL6665273 0.83 ACP3 (0.47) ACP3SRCANPEPLMNAGRIN2D
SCHEMBL6658782 0.83 NPSR1 (0.43) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6658790 0.83 NPSR1 (0.43) ACP3GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6667602 0.83 POLB (0.49) ACP3LMNAPOLB
SCHEMBL6665628 0.82 FDPS (0.44)
SCHEMBL6665624 0.82 FDPS (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0877028-B1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS HOKKO CHEM IND CO (JP) 2004-08-25 EP disclosed
US-6084123-A REACTING AN IMINE WITH A PHOSPHONIC ACID ESTER USING AN ASYMMETRIC CATALYST OF A RARE EARTH METAL/ALKALI METAL-BINAPHTHOL COMPLEX; HYDROGENATION AND ACIDOLYSIS HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 2000-07-04 US disclosed
EP-0877028-A1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) 1998-11-11 EP disclosed