SCHEMBL6661033

SCHEMBL6661033

Nc1ccc(NCc2nn(CCO)c(N)c2N)cc1CCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6665788 0.99
SCHEMBL6659239 0.84 ALDH1A1 (0.37)
Hydrochloric Acid SCHEMBL6665463 0.83 ALDH1A1 (0.36)
SCHEMBL6660450 0.81 KDM4E (0.32)
SCHEMBL6663221 0.81 MAOA (0.37)
Hydrochloric Acid SCHEMBL7243426 0.81 KDM4E (0.32)
SCHEMBL6659417 0.80 MEN1 (0.36)
Hydrochloric Acid SCHEMBL6659746 0.80 MAOA (0.36)
SCHEMBL6661175 0.79 ALDH1A1 (0.46)
SCHEMBL6658851 0.79 GAA (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1232509-C Diaminopyrazole derivatives and dyes containing these compounds P & G KRYROER CO (US) 2005-12-21 CN claimed
EP-1268436-B1 NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS WELLA AG (DE) 2004-08-18 EP claimed
CN-1441786-A Novel diamino pyrazole derivatives and dyes containing said compounds WELLA AG (DE) 2003-09-10 CN claimed
US-6600050-B2 Inorganic and organic acids and agents, containing these compounds, for the oxidative dyeing of fibers such as hair for hair dyes WELLA AG (DE) 2003-07-29 US claimed
US-20030115684-A1 Novel diaminopyrazole derivatives and dyes containing said compounds HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2003-06-26 US claimed
EP-1268436-A1 NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS Wella Aktiengesellschaft (DE) 2003-01-02 EP claimed
WO-2002072556-A1 NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 2002-09-19 WO claimed
CN-1232509-C Diaminopyrazole derivatives and dyes containing these compounds P & G KRYROER CO (US) 2005-12-21 CN disclosed
EP-1268436-B1 NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS WELLA AG (DE) 2004-08-18 EP disclosed
CN-1441786-A Novel diamino pyrazole derivatives and dyes containing said compounds WELLA AG (DE) 2003-09-10 CN disclosed
US-6600050-B2 Inorganic and organic acids and agents, containing these compounds, for the oxidative dyeing of fibers such as hair for hair dyes WELLA AG (DE) 2003-07-29 US disclosed
US-20030115684-A1 Novel diaminopyrazole derivatives and dyes containing said compounds HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2003-06-26 US disclosed
EP-1268436-A1 NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS Wella Aktiengesellschaft (DE) 2003-01-02 EP disclosed
WO-2002072556-A1 NOVEL DIAMINOPYRAZOLE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS WELLA AKTIENGESELLSCHAFT (DE) 2002-09-19 WO disclosed