Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | GALR1 | P47211 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13945071 | 0.76 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2EPHX2NPC1RAB9A | |
| SCHEMBL1241688 | 0.76 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2EPHX2NPC1RAB9A | |
| SCHEMBL28522679 | 0.73 | SMN1; SMN2 (0.64) | ALDH1A1SMN1; SMN2EPHX2NPC1RAB9A | |
| SCHEMBL29078140 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2EPHX2NPC1RAB9A | |
| SCHEMBL29078142 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2EPHX2NPC1RAB9A | |
| SCHEMBL9823117 | 0.70 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2EPHX2NPC1RAB9A | |
| SCHEMBL28419236 | 0.69 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2EPHX2NPC1RAB9A | |
| SCHEMBL674674 | 0.69 | RAB9A (0.59) | ALDH1A1SMN1; SMN2EPHX2NPC1RAB9A | |
| SCHEMBL9823120 | 0.69 | SMN1; SMN2 (0.48) | ALDH1A1SMN1; SMN2EPHX2NPC1RAB9A | |
| SCHEMBL28416149 | 0.68 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2EPHX2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877028-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEM IND CO (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6084123-A | REACTING AN IMINE WITH A PHOSPHONIC ACID ESTER USING AN ASYMMETRIC CATALYST OF A RARE EARTH METAL/ALKALI METAL-BINAPHTHOL COMPLEX; HYDROGENATION AND ACIDOLYSIS | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0877028-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |