Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27898247 | 0.85 | CYP1A2 (0.51) | RAB9AMEN1KMT2APOLBHDAC1 | |
| SCHEMBL10963431 | 0.84 | HDAC1 (0.50) | RAB9AMEN1KMT2APOLBHDAC1 | |
| SCHEMBL2723012 | 0.83 | MKNK1 (0.60) | HDAC1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3962151 | 0.79 | DAO (0.31) | — | |
| SCHEMBL2722295 | 0.78 | XDH (0.44) | KDM4EALDH1A1HPGDCYP2C9HSD17B1 | |
| SCHEMBL7812232 | 0.78 | KDM4E (0.59) | RAB9AKMT2APOLBHDAC1KDM4E | |
| SCHEMBL2411079 | 0.78 | CNR1 (0.45) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL2407370 | 0.75 | TSHR (0.39) | KMT2AKDM4EHPGDMAPK1HSD17B1 | |
| SCHEMBL29156695 | 0.74 | RAB9A (0.47) | RAB9AMEN1KMT2APOLBHDAC1 | |
| SCHEMBL5763046 | 0.74 | DAO (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0952154-B1 | N-acyl and N-aroyl aralkyl amides | PFIZER PROD INC (US) | 2004-08-18 | — | — | EP | claimed |