Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657144 | 0.90 | MEN1 (0.45) | GHSRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7169394 | 0.88 | GHSR (0.55) | GHSRLTB4RLTB4R2CTSBCTSS | |
| SCHEMBL7647039 | 0.87 | GHSR (0.63) | GHSRLTB4RLTB4R2CTSBCTSS | |
| SCHEMBL6659036 | 0.84 | GHSR (0.64) | GHSRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6659747 | 0.84 | GHSR (0.64) | GHSRKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6657445 | 0.84 | GHSR (0.52) | GHSRKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL7771304 | 0.84 | GHSR (0.52) | GHSRKDM4EALDH1A1KMT2ATDP1 | |
| SCHEMBL7648623 | 0.83 | GHSR (0.56) | GHSRLTB4RLTB4R2CTSBCTSS | |
| SCHEMBL7968541 | 0.83 | GHSR (0.56) | GHSRLTB4RLTB4R2CTSBCTSS | |
| SCHEMBL6317705 | 0.83 | GHSR (0.48) | GHSRCTSBCTSSCTSKMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127071-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-08-04 | — | — | EP | disclosed |
| US-6566337-B1 | Compounds with growth hormone releasing properties | NOVO NORDISK A/S (DK) | 2003-05-20 | — | — | US | disclosed |
| EP-1127071-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | Novo Nordisk A/S (DK) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000026252-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 2000-05-11 | — | — | WO | disclosed |