Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771304 | 1.00 | GHSR (0.52) | GHSRALDH1A1KDM4EMMP9MMP8 | |
| SCHEMBL8170611 | 0.85 | GHSR (0.54) | GHSRMMP9MMP8 | |
| SCHEMBL5879498 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EPTGFRKMT2ANPC1 | |
| SCHEMBL6656758 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EPTGFRKMT2ANPC1 | |
| SCHEMBL5879436 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EPTGFRKMT2ANPC1 | |
| SCHEMBL6661365 | 0.84 | GHSR (0.50) | GHSRALDH1A1KDM4EPTGFRKMT2A | |
| SCHEMBL8710705 | 0.83 | GHSR (0.52) | GHSRMMP9MMP8 | |
| SCHEMBL6320694 | 0.82 | MMP9 (0.56) | GHSRMMP9MMP8 | |
| SCHEMBL8235025 | 0.81 | GHSR (0.49) | GHSRMMP9MMP8 | |
| SCHEMBL3266844 | 0.80 | GHSR (0.48) | GHSRMMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127071-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-08-04 | — | — | EP | claimed |
| EP-1127071-B1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK AS (DK) | 2004-08-04 | — | — | EP | disclosed |
| US-6566337-B1 | Compounds with growth hormone releasing properties | NOVO NORDISK A/S (DK) | 2003-05-20 | — | — | US | disclosed |
| EP-1127071-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | Novo Nordisk A/S (DK) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000026252-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 2000-05-11 | — | — | WO | disclosed |