Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | AGXT | P21549 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL28823289 | 0.84 | IDO1 (0.61) | IDO1AGXTCA1CA2CALM1 | |
| SCHEMBL351810 | 0.84 | CA1 (0.58) | CA1CA2TDP1L3MBTL1ENPP2 | |
| SCHEMBL34413 | 0.84 | IDO1 (0.67) | IDO1AGXTCA1CA2CALM1 | |
| SCHEMBL4663332 | 0.84 | CA1 (0.38) | IDO1AGXTCA1CA2CALM1 | |
| SCHEMBL7928362 | 0.83 | CA1 (0.37) | IDO1AGXTCA1CA2HTT | |
| SCHEMBL6662818 | 0.83 | TSHR (0.58) | CA1CA2TDP1L3MBTL1POLB | |
| SCHEMBL7931547 | 0.82 | IDO1 (0.41) | IDO1AGXTCA1CA2CALM1 | |
| Bromide SCHEMBL28558295 | 0.82 | IDO1 (0.64) | IDO1AGXTCA1CA2CALM1 | |
| Potassium SCHEMBL1477050 | 0.82 | IDO1 (0.64) | IDO1AGXTCA1CA2CALM1 | |
| Methoxymethane SCHEMBL28823290 | 0.82 | IDO1 (0.64) | IDO1AGXTCA1CA2CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444981-A1 | INTRACELLULAR CALCIUM CONCENTRATION INCREASE INHIBITORS | Mikoshiba, Katsuhiko (JP) | 2004-08-11 | — | — | EP | disclosed |