Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660289 | 0.88 | TDP1 (0.50) | TSHRLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL4768663 | 0.88 | TDP1 (0.50) | TSHRLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL1373373 | 0.85 | LMNA (0.66) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL5370037 | 0.84 | TSHR (0.48) | TSHRLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL16320997 | 0.84 | LMNA (0.47) | TSHRLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL28077460 | 0.84 | LTA4H (0.55) | LMNACYP1A2CYP2C19LTA4HL3MBTL1 | |
| SCHEMBL6661512 | 0.83 | IDO1 (0.50) | HDAC6MAOBL3MBTL1TDP1CA1 | |
| SCHEMBL27781804 | 0.83 | LMNA (0.58) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL5373560 | 0.82 | TSHR (0.50) | TSHRLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL5377522 | 0.81 | TSHR (0.48) | TSHRLMNACYP1A2PTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230971-B | Boric acid and ester as inhibitors of fatty amide hydrolase | 英菲尼提制药公司 | 2017-11-24 | — | — | CN | disclosed |
| CN-101863913-B | Preparation method of fluorinated aryl-containing boron compound | SHANGHAI RES INST CHEMICAL IND | 2013-02-27 | — | — | CN | disclosed |
| CN-101863913-A | Preparation method of fluorinated aryl-containing boron compound | SHANGHAI RES INST CHEMICAL IND | 2010-10-20 | — | — | CN | disclosed |
| CN-101563089-A | Boronic acids and esters as inhibitors of fatty amide hydrolase | INFINITY DISCOVERY INC (US) | 2009-10-21 | — | — | CN | disclosed |
| EP-1444981-A1 | INTRACELLULAR CALCIUM CONCENTRATION INCREASE INHIBITORS | Mikoshiba, Katsuhiko (JP) | 2004-08-11 | — | — | EP | disclosed |
| EP-0743943-B1 | PYRIDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-10-31 | — | — | EP | disclosed |
| US-5849753-A | Pyridyl imidazole derivatives and processes for the preparation thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-12-15 | — | — | US | disclosed |
| EP-0743943-A1 | PYRIDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021838-A1 | PYRIDYL IMIDAZOLE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-08-17 | — | — | WO | disclosed |