SCHEMBL6661729

SCHEMBL6661729

CCOc1cccc2sc(S)nc12

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.69
KMT2A Q03164 7/20 0.64
MAPT P10636 6/20 0.64
KDM4E B2RXH2 5/20 0.64
MEN1 O00255 5/20 0.64
MAPK1 P28482 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
PKM P14618 1/20 0.64
HPGD P15428 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
DUSP3 P51452 1/20 0.49
HTT P42858 1/20 0.49
TP53 P04637 3/20 0.48
LMNA P02545 2/20 0.46
CYP3A4 P08684 1/20 0.45
HSD17B10 Q99714 1/20 0.45
THRB P10828 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
GAA P10253 1/20 0.42
RAD52 P43351 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6691012 0.87 ALDH1A1 (0.54) ALDH1A1KMT2AMAPTKDM4EMEN1
SCHEMBL6689421 0.86 ALDH1A1 (0.52) ALDH1A1KMT2AMAPTKDM4EMEN1
SCHEMBL2209697 0.83 ALDH1A1 (0.65) ALDH1A1KMT2AMAPTKDM4EMEN1
SCHEMBL3455462 0.82 TDP1 (0.69) ALDH1A1KMT2AMAPTKDM4EMEN1
SCHEMBL11443237 0.81 KDM4E (0.50) ALDH1A1KMT2AMAPTKDM4EMEN1
SCHEMBL6689165 0.81 ALDH1A1 (0.66) ALDH1A1KMT2AMAPTKDM4EMEN1
SCHEMBL6898848 0.81 ALDH1A1 (0.66) ALDH1A1KMT2AMAPTKDM4EMEN1
SCHEMBL2138791 0.78 ALDH1A1 (0.62) ALDH1A1KMT2AMAPTKDM4EMEN1
SCHEMBL2136477 0.78 MAPT (1.00) ALDH1A1KMT2AMAPTKDM4EMEN1
SCHEMBL8634248 0.78 ALDH1A1 (0.62) ALDH1A1KMT2AMAPTKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0276667-A2 Stabilized moisture curable polyurethane coatings Ashland Oil, Inc. (US) 1988-08-03 EP claimed
JP-2000868-A None JP disclosed
CN-1589420-A Method for improving sensitometric response of photosensitive imaging media employing microcapsules HSBC BANK U S A (US) 2005-03-02 CN disclosed
EP-1446701-A1 METHOD FOR IMPROVING SENSITOMETRIC RESPONSE OF PHOTOSENSITIVE IMAGING MEDIA EMPLOYING MICROCAPSULES HSBC Bank U.S.A. (US) 2004-08-18 EP disclosed
EP-0869016-B1 Pneumatic radial tires BRIDGESTONE CORP (JP) 2004-03-03 EP disclosed
EP-0945482-B1 Rubber composition for tire tread and pneumatic tire using same BRIDGESTONE CORP (JP) 2004-01-28 EP disclosed
US-6638678-B2 Method for improving sensitometric response of photosensitive imaging media employing microcapsules HSBC BANK USA 2003-10-28 US disclosed
US-20030124451-A1 Identification (ID) cards using a photosensitive imaging system employing microcapsules is described. In accordance with one aspect of the invention, ID cards are produced by translating an image containing identifying indicia into a HSBC BANK USA, AS TRUSTEE OF THE CYCOLOR, INC. 2003 TRUST U/A 2003-07-03 US disclosed
WO-2003044601-A1 METHOD FOR IMPROVING SENSITOMETRIC RESPONSE OF PHOTOSENSITIVE IMAGING MEDIA EMPLOYING MICROCAPSULES HSBC BANK USA (US) 2003-05-30 WO disclosed
US-20030096187-A1 Method for improving sensitometric response of photosensitive imaging media employing microcapsules HSBC BANK USA, AS TRUSTEE OF THE CYCOLOR, INC. 2003 TRUST U/A 2003-05-22 US disclosed
EP-0854168-A1 Rubber composition Bridgestone Corporation (JP) 1998-07-22 EP disclosed
EP-0318336-B1 Dye-sensitive photopolymerizable compositions CYCOLOR INC (US) 1997-05-21 EP disclosed
EP-0420225-A2 Photopolymer film for holography E.I. du Pont de Nemours and Company (US) 1991-04-03 EP disclosed
EP-0407771-A2 Holographic photopolymer compositions and elements for refractive index imaging E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-16 EP disclosed
EP-0407772-A2 Dry film process for altering wavelength response of holograms E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-01-16 EP disclosed
JP-H02868-A PHOTOPOLYMERIZABLE COMPOSITION BY PHOTOSENSITIVITY BY DYE MEAD CORP:THE 1990-01-05 JP disclosed
US-4874685-A Photocurable composition containing a photoreducible dye a thiol and an N,N'-dialkylaniline THE MEAD CORPORATION (US) 1989-10-17 US disclosed
CN-1033699-A The Photosetting component that contains photo-reduction dyestuff and mercaptan MEAD CORP (US) 1989-07-05 CN disclosed
EP-0318336-A2 Dye-sensitive photopolymerizable compositions THE MEAD CORPORATION (US) 1989-05-31 EP disclosed
EP-0276667-A2 Stabilized moisture curable polyurethane coatings Ashland Oil, Inc. (US) 1988-08-03 EP disclosed