Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.57 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.57 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663533 | 0.84 | SMN1; SMN2 (0.68) | NPSR1CSNK2A2CSNK2BCSNK2A1FGFR1 | |
| SCHEMBL6663303 | 0.84 | SMN1; SMN2 (0.68) | NPSR1CSNK2A2CSNK2BCSNK2A1FGFR1 | |
| SCHEMBL4553755 | 0.84 | FGFR1 (0.67) | CSNK2A2CSNK2BCSNK2A1FGFR1ALDH1A1 | |
| SCHEMBL3172318 | 0.84 | SMN1; SMN2 (0.50) | NPSR1CSNK2A2CSNK2BCSNK2A1FGFR1 | |
| SCHEMBL2368917 | 0.81 | MAPT (0.77) | NPSR1CSNK2A2CSNK2BCSNK2A1FGFR1 | |
| SCHEMBL6641938 | 0.81 | CCR1 (0.42) | NPSR1CSNK2A2CSNK2BCSNK2A1FGFR1 | |
| SCHEMBL3163264 | 0.76 | FGFR1 (0.49) | CSNK2A2CSNK2BCSNK2A1FGFR1ALDH1A1 | |
| SCHEMBL1604974 | 0.76 | MRGPRX1 (0.46) | NPSR1CSNK2A2CSNK2BCSNK2A1FGFR1 | |
| SCHEMBL24034414 | 0.75 | KMT2A (0.69) | NPSR1ALDH1A1L3MBTL1KMT2AMAPT | |
| SCHEMBL18292436 | 0.75 | HTT (0.61) | NPSR1CSNK2A2CSNK2BCSNK2A1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138238-A1 | Substituted aminopyrimidine compounds as neurokinin antagonists | PREDIX PHARMACEUTICALS HOLDINGS, INC. | 2004-07-15 | — | — | US | disclosed |
| WO-2004014850-A2 | SUBSTITUTED AMINOPYRIMIDINES AS NEUROKININ ANTAGONISTS | PREDIX PHARMACEUTICALS HOLDINGS, INC. (US) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138238-A1 | Substituted aminopyrimidine compounds as neurokinin antagonists | TACR1, GRPR, BDKRB1 | NPSR1 4/4885CSNK2A2 2323/4885CSNK2B 1684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.