Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | DRD4 | P21917 | 5/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29662230 | 1.00 | SLC2A1 (0.50) | SLC2A1MAPTDRD2DRD4GLA | |
| SCHEMBL3117879 | 0.92 | SLC2A1 (0.50) | SLC2A1MAPTDRD2DRD4KDM4E | |
| SCHEMBL3123342 | 0.92 | SLC2A1 (0.50) | SLC2A1MAPTDRD2DRD4KDM4E | |
| SCHEMBL6712456 | 0.90 | SLC2A1 (0.48) | SLC2A1MAPTDRD2DRD4KDM4E | |
| SCHEMBL3120197 | 0.90 | LMNA (0.49) | SLC2A1DRD2DRD4KDM4EHTT | |
| SCHEMBL3117184 | 0.89 | DRD2 (0.54) | SLC2A1DRD2DRD4DRD3DRD1 | |
| Hydrochloric Acid SCHEMBL6707202 | 0.88 | DRD2 (0.53) | SLC2A1DRD2DRD4DRD3DRD1 | |
| SCHEMBL3121723 | 0.85 | DRD2 (0.51) | SLC2A1DRD2DRD4DRD3DRD1 | |
| SCHEMBL6805753 | 0.83 | SLC2A1 (0.49) | SLC2A1MAPTDRD2DRD4KDM4E | |
| SCHEMBL6807063 | 0.83 | SLC2A1 (0.48) | SLC2A1MAPTDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040072865-A1 | Aryl piperidine derivatives as inducers of ldl-receptor expression | SMITHKLINE BEECHAM CORPORATION | 2004-04-15 | — | — | US | disclosed |
| WO-2004006935-A1 | USE OF COMPOUNDS THAT ACTIVATE THE STEROL REGULATORY ELEMENT BINDING PROTEIN (SREBP) PATHWAY | Austria Wirtschaftsservice Gesellschaft mit beschränkter Haftung (AT) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072865-A1 | Aryl piperidine derivatives as inducers of ldl-receptor expression | NR1H2, NR1H3, NR1H4 | SLC2A1 345/4885MAPT 4646/4885DRD2 269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.