Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 8/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759715 | 0.93 | MAPT (0.65) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| SCHEMBL6660033 | 0.78 | MAPT (0.56) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| Trifluoroacetic Acid SCHEMBL7065193 | 0.74 | MAPT (0.58) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| SCHEMBL6661677 | 0.74 | MAPT (1.00) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| Trifluoroacetic Acid SCHEMBL6664769 | 0.74 | MEN1 (0.46) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| Trifluoroacetic Acid SCHEMBL6665362 | 0.73 | MEN1 (0.50) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| Trifluoroacetic Acid SCHEMBL6659827 | 0.72 | MAPT (0.46) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| Trifluoroacetic Acid SCHEMBL6662164 | 0.71 | MEN1 (0.48) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| Trifluoroacetic Acid SCHEMBL6659833 | 0.71 | MAPT (0.50) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| Trifluoroacetic Acid SCHEMBL10689583 | 0.70 | KMT2A (0.41) | L3MBTL1MAPK1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087935-B1 | ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS | BTG INT LTD (GB) | 2004-08-18 | — | — | EP | disclosed |
| US-20030203975-A1 | Anti-cancer agents | BTG INTERNATIONAL LIMITED (GB) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203975-A1 | Anti-cancer agents | TOP2B, TOP2A, TOP1 | MAPT 4879/4885NPSR1 2757/4885L3MBTL1 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.