Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | HTR6 | P50406 | 6/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6661975 | 0.93 | MAPT (0.57) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| SCHEMBL6660033 | 0.82 | MAPT (0.56) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| SCHEMBL6661677 | 0.80 | MAPT (1.00) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| SCHEMBL2463193 | 0.70 | MAPT (1.00) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| SCHEMBL3273424 | 0.69 | MAPT (0.97) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| SCHEMBL10365727 | 0.68 | ADORA2B (0.55) | LMNAALDH1A1DRD2DRD3DRD4 | |
| SCHEMBL7290042 | 0.68 | DRD3 (0.48) | MAPTNPSR1KMT2ALMNAALDH1A1 | |
| SCHEMBL7063615 | 0.68 | DPP7 (0.52) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| SCHEMBL3418386 | 0.68 | MAPT (0.90) | MAPTNPSR1L3MBTL1TDP1EGFR | |
| SCHEMBL6660403 | 0.68 | MAPT (0.69) | MAPTNPSR1L3MBTL1TDP1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087935-A1 | ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS | BTG INTERNATIONAL LIMITED (GB) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065866-A1 | ANTHRACENE DERIVATIVES AS ANTI-CANCER AGENTS | BTG INTERNATIONAL LIMITED (GB) | 1999-12-23 | — | — | WO | disclosed |