SCHEMBL6661998

SCHEMBL6661998

CCCc1ccc(C(F)(F)OCCc2ccc(OC(F)F)c(F)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CACNA1H O95180 4/20 0.36
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
GLA P06280 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PTGES O14684 1/20 0.31
ALOX5 P09917 1/20 0.31
PPARG P37231 1/20 0.31
S1PR1 P21453 1/20 0.30
S1PR3 Q99500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6661852 0.92 CACNA1H (0.35) CACNA1HGLASMN1; SMN2PTGESALOX5
SCHEMBL6661295 0.92 CACNA1H (0.37) CACNA1HPPARDPPARA
SCHEMBL6664030 0.87 KMT2A (0.30)
SCHEMBL6666739 0.85 CACNA1H (0.36) CACNA1H
SCHEMBL7731646 0.85 CACNA1H (0.36) CACNA1HPTGESALOX5PPARGS1PR1
SCHEMBL6665130 0.83 TAAR1 (0.33) GLASMN1; SMN2
SCHEMBL6666020 0.83 ALDH1A1 (0.36) CACNA1H
SCHEMBL7732920 0.83 FFAR1 (0.36) CACNA1HPTGESALOX5PPARG
SCHEMBL6663307 0.82 PPARG (0.39) PPARAPPARG
SCHEMBL7729274 0.82 FFAR1 (0.36) CACNA1HPTGESALOX5PPARGS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed