SCHEMBL6665130

SCHEMBL6665130

CCCc1ccc(C(F)(F)OCCc2ccc(F)c(F)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.33
RIPK1 Q13546 1/20 0.33
PDK2 Q15119 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
KIF11 P52732 1/20 0.32
TP53 P04637 1/20 0.32
PKM P14618 1/20 0.32
HSD17B10 Q99714 1/20 0.32
DAO P14920 1/20 0.32
GAA P10253 1/20 0.32
IDO1 P14902 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6663942 0.91 HTR2A (0.40) TP53HSD17B10ALDH1A1
SCHEMBL6664131 0.90 KIF11 (0.33) TAAR1RIPK1KIF11DAOIDO1
SCHEMBL6662178 0.89 TAAR1 (0.33) TAAR1PDK2NPC1RAB9AKIF11
SCHEMBL6661122 0.88 TAAR1 (0.37) TAAR1KIF11IDO1ALDH1A1
SCHEMBL6667145 0.88 DAO (0.40) TAAR1PDK2KIF11DAOMAOB
SCHEMBL6665746 0.86 TAAR1 (0.35) TAAR1NPC1RAB9ADAOGAA
SCHEMBL6666739 0.85 CACNA1H (0.36)
SCHEMBL6661139 0.85 ALDH1A1 (0.41) TAAR1GAAIDO1ALDH1A1L3MBTL1
SCHEMBL6661244 0.84 DAO (0.39) DAO
SCHEMBL6663201 0.84 TAAR1 (0.30) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0893423-B1 LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES CHISSO CORP (JP) 2004-09-01 EP disclosed