Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668536 | 0.87 | HRH2 (0.61) | HRH2HRH3 | |
| SCHEMBL10667713 | 0.85 | HRH2 (0.37) | HRH2HRH3 | |
| SCHEMBL10401171 | 0.83 | HRH2 (0.54) | HRH2HRH3 | |
| SCHEMBL6662627 | 0.83 | MEN1 (0.41) | — | |
| SCHEMBL6657196 | 0.80 | MEN1 (0.57) | — | |
| SCHEMBL6656820 | 0.80 | DRD2 (0.54) | — | |
| SCHEMBL6662210 | 0.80 | MAPT (0.56) | — | |
| SCHEMBL6660189 | 0.79 | DRD2 (0.46) | HRH3 | |
| SCHEMBL9514920 | 0.78 | — | — | |
| SCHEMBL6659094 | 0.77 | MAOB (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |
| US-4952589-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1990-08-28 | — | — | US | disclosed |
| EP-0181163-B1 | HETEROCYCLIC PHENOXY DERIVATIVES HAVING AN ANTIHISTAMINE H2 ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1989-12-20 | — | — | EP | disclosed |
| US-4738969-A | Substituted aminopyridones and aminoquinolones having histamine H2 -receptor blocking activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1988-04-19 | — | — | US | disclosed |
| US-4681883-A | Histamine H2 -antagonist oxazole and thiazole derivatives and compositions therefor | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-07-21 | — | — | US | disclosed |
| US-4608380-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-08-26 | — | — | US | disclosed |
| EP-0181163-A2 | Heterocyclic phenoxy derivatives having an antihistamine H2 activity | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1986-05-14 | — | — | EP | disclosed |
| EP-0143630-A2 | Chemical compounds | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-06-05 | — | — | EP | disclosed |