Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 7/20 | 1.00 |
| ▸ | RARB | P10826 | 13/20 | 0.47 |
| ▸ | RARG | P13631 | 13/20 | 0.47 |
| ▸ | RARA | P10276 | 12/20 | 0.47 |
| ▸ | RXRA | P19793 | 5/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8796499 | 1.00 | PLA2G4A (1.00) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL8796502 | 1.00 | PLA2G4A (1.00) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL8796504 | 1.00 | PLA2G4A (1.00) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL6662339 | 1.00 | PLA2G4A (1.00) | PLA2G4ARARBRARGRARARXRA | |
| Bicarbonate SCHEMBL6673968 | 0.91 | PLA2G4A (0.83) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL9254004 | 0.82 | PLA2G4A (0.69) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL8795410 | 0.82 | PLA2G4A (0.69) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL9254001 | 0.82 | PLA2G4A (0.69) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL8795228 | 0.82 | PLA2G4A (0.69) | PLA2G4ARARBRARGRARARXRA | |
| SCHEMBL9254010 | 0.82 | PLA2G4A (0.69) | PLA2G4ARARBRARGRARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3875078-A1 | COMPOUNDS FOR THE TREATMENT OF COVID-19 | Dompe' Farmaceutici S.P.A. (IT) | 2021-09-08 | — | — | EP | claimed |
| EP-0857488-B1 | Compositions for enhancing skin permeation of drugs using permeation enhancers | BRISTOL MYERS SQUIBB CO (US) | 2004-07-21 | — | — | EP | claimed |
| US-6019988-A | COMPOSITIONS ARE PHYSICALLY SEPARATED UNTIL APPLICATION TO A BODY OR SKIN SURFACE AND ARE TOPICALLY APPLIED, EITHER AT THE SAME TIME, OR SEQUENTIALLY WITHIN A SHORT TIME OF EACH OTHER | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-02-01 | — | — | US | claimed |
| EP-0857488-A2 | Methods and compositions for enhancing skin permeation of drugs using permeation enhancers | Bristol-Myers Squibb Company (US) | 1998-08-12 | — | — | EP | claimed |
| EP-0629604-B1 | Alicyclic phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | claimed |
| EP-0701817-A2 | Medicaments for treating vascular leak syndrome | Bristol-Myers Squibb Company (US) | 1996-03-20 | — | — | EP | claimed |
| JP-11158060-A | — | — | None | — | — | JP | disclosed |
| EP-3875078-A1 | COMPOUNDS FOR THE TREATMENT OF COVID-19 | Dompe' Farmaceutici S.P.A. (IT) | 2021-09-08 | — | — | EP | disclosed |
| EP-0857488-B1 | Compositions for enhancing skin permeation of drugs using permeation enhancers | BRISTOL MYERS SQUIBB CO (US) | 2004-07-21 | — | — | EP | disclosed |
| US-6019988-A | COMPOSITIONS ARE PHYSICALLY SEPARATED UNTIL APPLICATION TO A BODY OR SKIN SURFACE AND ARE TOPICALLY APPLIED, EITHER AT THE SAME TIME, OR SEQUENTIALLY WITHIN A SHORT TIME OF EACH OTHER | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-02-01 | — | — | US | disclosed |
| JP-H11158060-A | METHOD AND COMPOSITION FOR INCREASING TRANSDERMAL PERMEATION OF DRUGS BY USING PERMEATION ENHANCER IN THE CASE THAT THE DRUGS AND/OR THE PERMEATION ENHANCER IS UNSTABLE IN THE COMPOSITION TO BE STORED FOR LONG PERIOD OF TIME | BRISTOL MYERS SQUIBB CO | 1999-06-15 | — | — | JP | disclosed |
| EP-0857488-A2 | Methods and compositions for enhancing skin permeation of drugs using permeation enhancers | Bristol-Myers Squibb Company (US) | 1998-08-12 | — | — | EP | disclosed |
| EP-0629604-B1 | Alicyclic phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5436369-A | Alicyclic phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-25 | — | — | US | disclosed |
| EP-0629604-A2 | Alicyclic phospholipase A2 inhibitors | Bristol-Myers Company (US) | 1994-12-21 | — | — | EP | disclosed |