SCHEMBL6662375

SCHEMBL6662375

CCC1(CCl)NC(=O)NC1=O

nearest known ligand 0.75

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
PDE7A Q13946 1/20 0.39
ADAM17 P78536 1/20 0.36
ADAMTS5 Q9UNA0 4/20 0.36
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP3A4 P08684 1/20 0.33
GABRB3 P28472 1/20 0.33
OPRD1 P41143 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
MMP14 P50281 2/20 0.31
MMP2 P08253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10565362 0.86 LMNA (0.33) LMNAADAM17ADAMTS5ALDH1A1MMP2
SCHEMBL1404437 0.86 LMNA (0.50) LMNAPDE7AADAM17ADAMTS5ALDH1A1
SCHEMBL27758977 0.83 LMNA (0.40) LMNAPDE7AADAM17ADAMTS5ALDH1A1
SCHEMBL24928304 0.78 LMNA (0.43) LMNAPDE7AADAM17ADAMTS5ALDH1A1
SCHEMBL6699900 0.78 PDE7A (0.44) LMNAPDE7AADAM17ADAMTS5ALDH1A1
SCHEMBL632189 0.78 LMNA (0.43) LMNAPDE7AADAM17ADAMTS5ALDH1A1
SCHEMBL5956035 0.78
Hydrochloric Acid SCHEMBL29874227 0.77 LMNA (0.41) LMNAPDE7AADAM17ADAMTS5ALDH1A1
Hydrochloric Acid SCHEMBL23354351 0.77 LMNA (0.41) LMNAPDE7AADAM17ADAMTS5ALDH1A1
SCHEMBL73830 0.76 LMNA (0.38) LMNAPDE7AADAM17ADAMTS5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101802317-B Cageless dispensing device RECKITT BENCKISER INC 2012-10-31 CN disclosed
CN-102076916-A Method for production of dispensing devices RECKITT BENCKISER INC 2011-05-25 CN disclosed
CN-102076917-A Dispensing device for toilet bowl RECKITT BENCKISER INC 2011-05-25 CN disclosed
CN-101802316-A Improvements in lavatory treatment devices RECKITT BENCKISER INC 2010-08-11 CN disclosed
CN-101802317-A Cageless dispensing device RECKITT BENCKISER INC 2010-08-11 CN disclosed
CN-1813111-A Improved release device RECKITT BENCKISER INC (US) 2006-08-02 CN disclosed
WO-2004018581-A2 RESIN CURING AGENTS, COMPOSITIONS AND PRODUCTS CONTAINING SAME BIOLAB, INC. (US) 2004-03-04 WO disclosed
US-6319356-B1 INHIBITING AUTOXIDATION OF UNSATURATED FATTY ACIDS AND/OR ESTERS IN PULP FIBER; OXIDIZATION BY ADDITION OF A HALOHYDANTOIN GREAT LAKES CHEMICAL CORPORATION 2001-11-20 US disclosed
EP-1095185-A4 PROCESS FOR CONTROLLING ODOR IN PAPER AND PAPERBOARD GREAT LAKES CHEMICAL CORP (US) 2001-10-17 EP disclosed
EP-1095185-A1 PROCESS FOR CONTROLLING ODOR IN PAPER AND PAPERBOARD GREAT LAKES CHEMICAL CORPORATION (US) 2001-05-02 EP disclosed
WO-1999058759-A1 PROCESS FOR CONTROLLING ODOR IN PAPER AND PAPERBOARD GREAT LAKES CHEMICAL CORPORATION (US) 1999-11-18 WO disclosed