SCHEMBL1404437

SCHEMBL1404437

CCC1(CC)NC(=O)NC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
PDE7A Q13946 1/20 0.43
ADAM17 P78536 1/20 0.39
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP3A4 P08684 1/20 0.38
GABRB3 P28472 1/20 0.38
OPRD1 P41143 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38
ADAMTS5 Q9UNA0 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL632189 0.86 LMNA (0.43) LMNAPDE7AADAM17ALDH1A1KDM4E
SCHEMBL6699900 0.86 PDE7A (0.44) LMNAPDE7AADAM17ALDH1A1KDM4E
SCHEMBL6662375 0.86 LMNA (0.43) LMNAPDE7AADAM17ALDH1A1KDM4E
SCHEMBL24928304 0.86 LMNA (0.43) LMNAPDE7AADAM17ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL29874227 0.84 LMNA (0.41) LMNAPDE7AADAM17ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL23354351 0.84 LMNA (0.41) LMNAPDE7AADAM17ALDH1A1KDM4E
SCHEMBL6692266 0.83 LMNA (0.40) LMNAPDE7AALDH1A1KDM4ECYP3A4
SCHEMBL6693034 0.83 LMNA (0.40) LMNAPDE7AADAM17ALDH1A1KDM4E
SCHEMBL11167483 0.81 MMP2 (0.42) LMNAADAMTS5TDP1
SCHEMBL12378773 0.81 ADAMTS5 (0.42) LMNAPDE7AADAM17ALDH1A1ADAMTS5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116960199-B Manufacturing method of metal grid line electrode on heterojunction solar cell 上海昕沐化学科技有限公司 2023-12-01 CN claimed
CN-116960199-A Manufacturing method of metal grid line electrode on heterojunction solar cell 上海昕沐化学科技有限公司 2023-10-27 CN claimed
CN-113215628-B Electroplating solution and application thereof 广东宇豪新材料科技有限公司 2022-11-08 CN claimed
CN-113089044-B Plastic shell metallization electroplating method and wear-resistant plastic 广东宇豪新材料科技有限公司 2022-07-12 CN claimed
CN-109852004-B Epoxy resin matrix composition, epoxy resin matrix and preparation method thereof 恩莱登(北京)工业技术有限公司 2022-03-04 CN claimed
CN-113215628-A Electroplating solution and application thereof 广东宇豪新材料科技有限公司 2021-08-06 CN claimed
CN-113089044-A Plastic shell metallization electroplating method and wear-resistant plastic 广东宇豪新材料科技有限公司 2021-07-09 CN claimed
CN-109457238-B High-speed stable chemical copper plating solution and preparation method thereof 上海昕沐化学科技有限公司 2021-01-15 CN claimed
CN-104105687-B The method for preparing N (trifluoromethyl benzyloxy of 4 cyclohexyl 3) second imido acetoacetic ester 诺华股份有限公司 2018-01-02 CN claimed
WO-2009120747-A1 METHODS OF REDUCING OR ELIMINATING BACTERIA IN CONSUMABLE EGGS ALBEMARLE CORPORATION (US) 2009-10-01 WO claimed
EP-1191849-B1 N-CHLOROSULFAMATE COMPOSITIONS HAVING ENHANCED ANTIMICROBIAL EFFICACY JOHNSON & SON INC S C (US) 2003-04-09 EP claimed
US-6471974-B1 STABILIZED HYPOCHLORITE SOLUTION OF A BUFFERED AQUEOUS COMBINATION OF MONO-N-CHLOROSULFAMATE (HCLNSO3-) AND DI-N-CHLOROSULFAMATE (CL2 NSO3-), A DIALKYL HYDANTOIN, AN ARYL SULFONAMIDE, AND A SUCCINIMIDE S.C. JOHNSON & SON, INC. 2002-10-29 US claimed
EP-1191849-A1 N-CHLOROSULFAMATE COMPOSITIONS HAVING ENHANCED ANTIMICROBIAL EFFICACY S. C. Johnson & Son, Inc. (US) 2002-04-03 EP claimed
WO-2001000029-A1 N-CHLOROSULFAMATE COMPOSITIONS HAVING ENHANCED ANTIMICROBIAL EFFICACY S. C. JOHNSON & SON, INC. (US) 2001-01-04 WO claimed
EP-0785192-B1 Stabilization of halogenated hydantoins BROMINE COMPOUNDS LTD (IL) 2000-05-10 EP claimed
US-5780641-A MIXING WITH DRY CALCIUM HYDROXIDE; STORAGE STABILITY BROMINE COMPOUNDS LTD. (IL) 1998-07-14 US claimed
EP-0785192-A1 Stabilization of halogenated hydantoins Bromine Compounds Ltd. (IL) 1997-07-23 EP claimed
EP-0534774-A1 5,5-Dialkyl hydantoins for promoted acid gas scrubbing processes EXXON CHEMICAL PATENTS INC. (US) 1993-03-31 EP claimed
US-4654424-A CONTROLLING PH GLYCO INC. (US) 1987-03-31 US claimed
US-4537697-A Method of enhancing solubility of halogenated hydantoins GLYCO, INC. (US) 1985-08-27 US claimed