Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 12/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665622 | 0.83 | ESR1 (0.48) | DHODHMEN1KMT2AESR1ESR2 | |
| SCHEMBL8956235 | 0.83 | DHODH (0.49) | DHODHESR1ESR2 | |
| SCHEMBL3928076 | 0.82 | DHODH (0.50) | DHODHMEN1KMT2AESR1ESR2 | |
| SCHEMBL6662145 | 0.80 | DHODH (0.56) | DHODHADORA2A | |
| SCHEMBL7155536 | 0.79 | KMT2A (0.69) | DHODHMEN1KMT2AESR2 | |
| SCHEMBL9692642 | 0.79 | KMT2A (0.69) | DHODHMEN1KMT2AESR2 | |
| SCHEMBL6661826 | 0.78 | ADORA2A (0.53) | DHODHMEN1KMT2AADORA2A | |
| SCHEMBL6663355 | 0.77 | MEN1 (0.53) | DHODHMEN1KMT2AESR1ESR2 | |
| SCHEMBL8956269 | 0.75 | KDM4E (0.58) | DHODHADORA2A | |
| SCHEMBL6662078 | 0.75 | ESR1 (0.73) | DHODHMEN1KMT2AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861864-B1 | Method of preparation of polyquinolines | HITACHI CHEMICAL CO LTD (JP) | 2004-08-25 | — | — | EP | disclosed |
| EP-0861864-A2 | Method of preparation of polyquinolines | HITACHI CHEMICAL CO., LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5786071-A | Method of preparation of polyquinolines | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| US-5723573-A | ACETYLENIC END GROUPS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5648448-A | Method of preparation of polyquinolines | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-07-15 | — | — | US | disclosed |