Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 7/20 | 0.50 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662145 | 0.87 | DHODH (0.56) | ADORA2ALMNADHODH | |
| SCHEMBL8956276 | 0.79 | KDM4E (0.58) | ADORA2ALMNADHODHPRKAA2MAPK10 | |
| SCHEMBL8956269 | 0.79 | KDM4E (0.58) | ADORA2ALMNADHODHPRKAA2MAPK10 | |
| SCHEMBL28027827 | 0.78 | ADORA2A (0.53) | ADORA2ALMNADHODHPRKAA2PDE10A | |
| SCHEMBL6662378 | 0.78 | DHODH (0.50) | ADORA2ADHODHMEN1KMT2A | |
| SCHEMBL28215884 | 0.77 | MAPK14 (0.75) | ADORA2ALMNAMAPK10MAPK14MEN1 | |
| SCHEMBL28232225 | 0.76 | ADORA2A (0.67) | ADORA2AMAPK10MAPK14KMT2ASCN9A | |
| SCHEMBL3434573 | 0.76 | DHODH (0.66) | ADORA2ALMNADHODHPDE10AMEN1 | |
| SCHEMBL6661091 | 0.76 | DHODH (0.50) | DHODH | |
| Benzene SCHEMBL8658654 | 0.75 | ADORA2A (0.49) | ADORA2ALMNADHODHPRKAA2MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861864-B1 | Method of preparation of polyquinolines | HITACHI CHEMICAL CO LTD (JP) | 2004-08-25 | — | — | EP | disclosed |
| EP-0861864-A2 | Method of preparation of polyquinolines | HITACHI CHEMICAL CO., LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5786071-A | Method of preparation of polyquinolines | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| US-5723573-A | ACETYLENIC END GROUPS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5648448-A | Method of preparation of polyquinolines | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-07-15 | — | — | US | disclosed |