Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133131 | 0.85 | IKBKB (0.54) | IKBKBHSD17B1HSD17B2CYP2A6TDP1 | |
| SCHEMBL9681001 | 0.79 | IKBKB (0.53) | IKBKBHSD17B1HSD17B2CYP2A6TDP1 | |
| SCHEMBL3358215 | 0.77 | ALOX5 (0.52) | IKBKBHSD17B1HSD17B2CYP2A6TDP1 | |
| SCHEMBL16670765 | 0.76 | CYP2C9 (0.55) | IKBKBCYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL28441429 | 0.75 | ERN1 (0.50) | IKBKBHSD17B1HSD17B2CYP2A6TDP1 | |
| SCHEMBL1133224 | 0.74 | CYP2A6 (0.54) | IKBKBHSD17B1HSD17B2CYP2A6TDP1 | |
| SCHEMBL260950 | 0.72 | IKBKB (0.49) | IKBKBHSD17B1HSD17B2CYP2A6TDP1 | |
| SCHEMBL29416662 | 0.72 | IKBKB (0.49) | IKBKBHSD17B1HSD17B2CYP2A6TDP1 | |
| SCHEMBL20598295 | 0.71 | IKBKB (0.49) | IKBKBHSD17B1HSD17B2CYP2A6TDP1 | |
| SCHEMBL3678817 | 0.71 | IKBKB (0.51) | IKBKBHSD17B1HSD17B2CYP2A6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004011473-A1 | ORGANOGERMANIUM COMPOUNDS AND METHODS FOR THEIR USE | CHIROGEN PTY LIMITED (AU) | 2004-02-05 | — | — | WO | disclosed |