SCHEMBL16670765

SCHEMBL16670765

Cc1cccc(C(=O)O)c1-c1ccc2ccccc2c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
TSHR P16473 1/20 0.55
CYP2C19 P33261 1/20 0.55
SOS1 Q07889 1/20 0.55
HIF1A Q16665 1/20 0.55
FABP4 P15090 2/20 0.54
FABP3 P05413 1/20 0.54
FABP5 Q01469 1/20 0.54
MYC P01106 1/20 0.54
ACMSD Q8TDX5 1/20 0.54
CTRC Q99895 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
SLC6A3 Q01959 1/20 0.47
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9009356 0.89 ACMSD (0.62) CYP2C9CYP1A2CYP2D6TSHRCYP2C19
SCHEMBL8669703 0.84 CYP1A2 (0.55) CYP2C9CYP1A2CYP2D6TSHRCYP2C19
SCHEMBL27510744 0.82 CYP1A2 (0.56) CYP2C9CYP1A2CYP2D6TSHRCYP2C19
SCHEMBL4363981 0.81 FABP4 (0.68) CYP2C9CYP1A2HIF1AFABP4FABP3
SCHEMBL1133131 0.81 IKBKB (0.54) CYP2C9CYP1A2TSHRKDM4EALDH1A1
SCHEMBL27533883 0.81 ACMSD (0.57) CYP2C9CYP1A2CYP2D6TSHRCYP2C19
Hydrochloric Acid SCHEMBL7605502 0.80 FABP4 (0.66) CYP2C9CYP1A2HIF1AFABP4FABP3
SCHEMBL17500264 0.79 DHODH (0.48) FABP4MYCKDM4EALDH1A1HPGD
SCHEMBL4986456 0.78 MYC (0.58) CYP2C9CYP1A2HIF1AFABP4MYC
SCHEMBL8030330 0.78 CYP1A2 (0.51) CYP2C9CYP1A2CYP2D6TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015061198-A1 BLUE LUMINESCENT COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2015-04-30 WO disclosed