Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | HTR2B | P41595 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.40 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800573 | 0.92 | ROCK2 (0.52) | ROCK2SMOHTR2CHTR2BHTR2A | |
| SCHEMBL6666579 | 0.92 | EIF2AK3 (0.46) | ROCK2SMOHTR2CHTR2BHTR2A | |
| SCHEMBL6667760 | 0.87 | EIF2AK3 (0.47) | ROCK2SMOHTR2CHTR2BHTR2A | |
| SCHEMBL6663993 | 0.86 | EIF2AK3 (0.50) | ROCK2SMOHTR2CHTR2BHTR2A | |
| SCHEMBL6664314 | 0.86 | SMO (0.47) | SMOHTR2CHTR2BHTR2AEIF2AK3 | |
| SCHEMBL6665157 | 0.86 | SMO (0.49) | SMOHTR2CHTR2BHTR2AEIF2AK3 | |
| SCHEMBL6664878 | 0.86 | EIF2AK3 (0.48) | SMOHTR2CHTR2BHTR2AEIF2AK3 | |
| SCHEMBL6661936 | 0.86 | SMO (0.47) | SMOHTR2CHTR2BHTR2AEIF2AK3 | |
| SCHEMBL6664409 | 0.86 | EIF2AK3 (0.48) | SMOHTR2CHTR2BHTR2AEIF2AK3 | |
| SCHEMBL6809248 | 0.85 | SMO (0.56) | SMOHTR2CHTR2BHTR2AEIF2AK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |