Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 6/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18300001 | 0.86 | ERN1 (0.40) | ERN1CYP2A6PRKDCALDH1A1MEN1 | |
| SCHEMBL11993044 | 0.86 | ERN1 (0.44) | ERN1CYP2A6PRKDCALDH1A1LMNA | |
| SCHEMBL1390662 | 0.82 | ERN1 (0.46) | ERN1MAPT | |
| SCHEMBL31184476 | 0.82 | ERN1 (0.38) | ERN1PRKDCALDH1A1MAPTHPGD | |
| SCHEMBL7864192 | 0.82 | ERN1 (0.50) | ERN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29743687 | 0.82 | ERN1 (0.46) | ERN1MAPT | |
| SCHEMBL15748351 | 0.82 | ERN1 (0.38) | ERN1PRKDCALDH1A1 | |
| SCHEMBL30600412 | 0.81 | ERN1 (0.50) | ERN1CYP2A6PRKDCALDH1A1LMNA | |
| SCHEMBL7864198 | 0.79 | ERN1 (0.66) | ERN1PRKDCALDH1A1LMNAMAPT | |
| SCHEMBL700676 | 0.79 | L3MBTL1 (0.40) | ERN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642689-B | 3, 6-dibromo-2-methylbenzaldehyde and chemical synthesis method thereof | 南通大学 | 2022-06-24 | — | — | CN | claimed |
| CN-110642689-A | 3, 6-dibromo-2-methylbenzaldehyde and chemical synthesis method thereof | 南通大学 | 2020-01-03 | — | — | CN | claimed |
| CN-110642689-B | 3, 6-dibromo-2-methylbenzaldehyde and chemical synthesis method thereof | 南通大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-110642689-B | 3, 6-dibromo-2-methylbenzaldehyde and chemical synthesis method thereof | 南通大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-110642689-B | 3, 6-dibromo-2-methylbenzaldehyde and chemical synthesis method thereof | 南通大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-110642689-A | 3, 6-dibromo-2-methylbenzaldehyde and chemical synthesis method thereof | 南通大学 | 2020-01-03 | — | — | CN | disclosed |
| CN-110642689-A | 3, 6-dibromo-2-methylbenzaldehyde and chemical synthesis method thereof | 南通大学 | 2020-01-03 | — | — | CN | disclosed |
| CN-110642689-A | 3, 6-dibromo-2-methylbenzaldehyde and chemical synthesis method thereof | 南通大学 | 2020-01-03 | — | — | CN | disclosed |
| EP-1131307-B1 | METHOD OF PRODUCING 2-ALKYL-3-(4,5-DIHYDROISOXAZOLE-3-YL)-HALOBENZENES | BASF AG (DE) | 2004-08-25 | — | — | EP | disclosed |
| US-6716989-B2 | CYCLIZATION OF A BENZYLOXIME WITH BRANCHED ALKENE OR OF A BENZALKYLALDEHYDE WITH HYDROXYLAMINE AND SULFIDING | BASF AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | disclosed |
| US-20030229232-A1 | Herbicides | RACK MICHAEL (DE) | 2003-12-11 | — | — | US | disclosed |
| US-6603017-B2 | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-05 | — | — | US | disclosed |
| US-6548677-B1 | Halogenating o-xylene; reacting with hydrogen peroxide and halogenating agent to form a benzyl halide; oxidation to aldehyde; oximination, cyclization, and sulfiding | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-15 | — | — | US | disclosed |
| US-20020156290-A1 | Herbicides | RACK MICHAEL (DE) | 2002-10-24 | — | — | US | disclosed |
| EP-1131307-A1 | METHOD OF PRODUCING 2-ALKYL-3-(4,5-DIHYDROISOXAZOLE-3-YL)-HALOBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029395-A1 | METHOD OF PRODUCING 2-ALKYL-3-(4,5-DIHYDROISOXAZOLE-3-YL)-HALOBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156290-A1 | Herbicides | CBR3, CBR1, SULT1E1 | ERN1 1730/4885CYP2A6 36/4885PRKDC 3657/4885 |
| US-20030229232-A1 | Herbicides | CBR3, CBR1, SULT1E1 | ERN1 1630/4885CYP2A6 39/4885PRKDC 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.