SCHEMBL30600412

SCHEMBL30600412

O=Cc1c(Br)ccc(Br)c1C=O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 7/20 0.50
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
PRKDC P78527 1/20 0.36
CYP2A6 P11509 3/20 0.35
LMNA P02545 2/20 0.33
PADI4 Q9UM07 1/20 0.33
THRB P10828 1/20 0.33
BLM P54132 1/20 0.33
TRIM24 O15164 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32
CA2 P00918 1/20 0.32
HSP90AA1 P07900 1/20 0.32
TLR9 Q9NR96 1/20 0.32
HSD11B1 P28845 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6900813 0.85 ERN1 (0.45) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL610877 0.81 ALDH1A1 (0.48) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL1418396 0.81 ERN1 (0.42) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL14486780 0.81 ERN1 (0.47) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL29504018 0.81 ERN1 (0.42) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL6662766 0.81 ERN1 (0.47) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL29080257 0.78 ERN1 (0.44) ERN1ALDH1A1LMNA
SCHEMBL23647903 0.77 ALDH1A1 (0.44) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL11993044 0.77 ERN1 (0.44) ERN1ALDH1A1MEN1KMT2ATDP1
SCHEMBL8471859 0.77 ERN1 (0.58) ERN1PADI4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116940559-A Cyclic diol compound, process for producing the compound, and use of the compound 新日本理化株式会社 2023-10-24 CN disclosed
CN-116829618-A Thermoplastic resin and optical lens comprising the same 三菱瓦斯化学株式会社 2023-09-29 CN disclosed