SCHEMBL6662779

SCHEMBL6662779

O=C1C2=CC=CC(=S)C2Oc2ccccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.36
PKM P14618 1/20 0.35
TSHR P16473 1/20 0.35
NPSR1 Q6W5P4 2/20 0.34
MAPT P10636 2/20 0.34
ADORA3 P0DMS8 3/20 0.33
MAOB P27338 3/20 0.33
AR P10275 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TTK P33981 1/20 0.32
MAPK8 P45983 1/20 0.32
MAPK9 P45984 1/20 0.32
MAPK10 P53779 1/20 0.32
PARP1 P09874 1/20 0.31
STK17B O94768 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6049871 0.84 CYP19A1 (0.38) CYP19A1PKMTSHRNPSR1MAPT
SCHEMBL4619988 0.74 CYP19A1 (0.37) CYP19A1PKMTSHRNPSR1MAPT
SCHEMBL1197981 0.70 MAPT (0.40) NPSR1MAPTKDM4ELMNACYP1A2
SCHEMBL28414163 0.69 CYP19A1 (0.54) CYP19A1PKMTSHRNPSR1MAPT
SCHEMBL8663560 0.68 KDM4E (0.30) CYP19A1ADORA3MAOBARKDM4E
SCHEMBL4621136 0.65 RET (0.31) RETKDR
SCHEMBL8858887 0.64 CYP19A1 (0.55) CYP19A1PKMTSHRNPSR1MAPT
SCHEMBL29411755 0.64 CYP19A1 (0.55) CYP19A1PKMTSHRNPSR1MAPT
Hydrochloric Acid SCHEMBL30559575 0.62 CYP19A1 (0.54) CYP19A1PKMTSHRNPSR1MAPT
SCHEMBL18769811 0.61 TTK (0.41) NPSR1MAPTADORA3KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114853708-A Method for preparing 4-thioflavone compound from hydroxychalcone compound and xanthate 苏州大学 2022-08-05 CN claimed
CN-116836621-A Photocurable composition, hard coating material, cured product, substrate with cured product, and image display device 株式会社力森诺科 2023-10-03 CN disclosed
CN-116806249-A Adhesive composition, adhesive sheet, method for producing adhesive composition, and method for detecting presence of water or water vapor 日东电工株式会社 2023-09-26 CN disclosed
CN-114072367-B Interlayer film for laminated glass and laminated glass 积水化学工业株式会社 2023-09-22 CN disclosed
CN-116162209-A Curable resin composition 大赛璐-湛新株式会社 2023-05-26 CN disclosed
CN-116009358-A Method for preparing photoresist-graphene conductive composite system, conductive composite system obtained by same and application thereof 北京师范大学 2023-04-25 CN disclosed
CN-114853708-A Method for preparing 4-thioflavone compound from hydroxychalcone compound and xanthate 苏州大学 2022-08-05 CN disclosed
CN-114853708-A Method for preparing 4-thioflavone compound from hydroxychalcone compound and xanthate 苏州大学 2022-08-05 CN disclosed
CN-112752650-A Intermediate laminate, method for producing same, laminate, and light-transmitting cover material 株式会社可乐丽 2021-05-04 CN disclosed
CN-104428331-A Active energy ray-polymerizable resin composition and laminate obtained using resin composition TOYO INK SC HOLDINGS CO LTD 2015-03-18 CN disclosed
CN-100551923-C Friedel-crafts process for the preparation of thioxanthones PROM LTD (GB) 2009-10-21 CN disclosed
CN-101037529-A Photosensitive thermosetting resin composition, flattened and resist film coated printed wiring board and method of preparing the same SAN EI KAGAKU K K (JP) 2007-09-19 CN disclosed
EP-1334096-B1 FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES PROM LTD (GB) 2004-07-28 EP disclosed
CN-1461302-A Friedel-crafts process for the preparation of thioxanthones PROM LTD (GB) 2003-12-10 CN disclosed
EP-1334096-A1 FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES Prom Limited (GB) 2003-08-13 EP disclosed
WO-2002040464-A1 FRIEDEL-CRAFT PROCESS FOR THE PREPARATION OF THIOXANTHONES PROM LIMITED (GB) 2002-05-23 WO disclosed
EP-0934247-A1 PHOTOINITIATORS Lambson Fine Chemicals Limited (GB) 1999-08-11 EP disclosed
WO-1997049664-A1 PHOTOINITIATORS LAMBSON FINE CHEMICALS LIMITED (GB) 1997-12-31 WO disclosed