SCHEMBL8663560

SCHEMBL8663560

C=C1C=CC=C2c3ccccc3OC12

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.30
ADORA3 P0DMS8 1/20 0.30
AR P10275 1/20 0.30
CYP19A1 P11511 1/20 0.30
MAOB P27338 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4619988 0.79 CYP19A1 (0.37) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL4621136 0.76 RET (0.31)
SCHEMBL6049871 0.70 CYP19A1 (0.38) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL6662779 0.68 CYP19A1 (0.36) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL600651 0.67 KDM4E (0.33) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL18371749 0.65
SCHEMBL6410680 0.64 KDM4E (0.32) KDM4EADORA3ARCYP19A1MAOB
SCHEMBL21587092 0.64
SCHEMBL9856224 0.63 KDM4E (0.32) KDM4E
SCHEMBL21546208 0.63 KDM4E (0.31) KDM4EADORA3ARCYP19A1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0667029-B1 THIXOTROPIC MAGNETORHEOLOGICAL MATERIALS LORD CORP (US) 1998-09-23 EP disclosed
US-5645752-A Thixotropic magnetorheological materials LORD CORPORATION (US) 1997-07-08 US disclosed
EP-0667029-A1 THIXOTROPIC MAGNETORHEOLOGICAL MATERIALS LORD CORPORATION (US) 1995-08-16 EP disclosed
EP-0667029-A4 THIXOTROPIC MAGNETORHEOLOGICAL MATERIALS. LORD CORP (US) 1995-06-13 EP disclosed
WO-1994010693-A1 THIXOTROPIC MAGNETORHEOLOGICAL MATERIALS LORD CORPORATION (US) 1994-05-11 WO disclosed