Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 2/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666038 | 0.92 | TRPV4 (0.34) | HSD17B10KDM4EALDH1A1TRPV4 | |
| SCHEMBL6663192 | 0.88 | CYP2A6 (0.35) | TRPV4 | |
| SCHEMBL6666053 | 0.87 | TSHR (0.39) | HSD17B10TSHRHTR2AFAAHRARB | |
| SCHEMBL6662863 | 0.87 | HTR2A (0.40) | HSD17B10HTR2AFAAHRARBRARA | |
| SCHEMBL7730411 | 0.85 | HSD17B10 (0.39) | HSD17B10TSHRHTR2AFAAHRARB | |
| SCHEMBL6661191 | 0.84 | HTR2A (0.38) | HSD17B10HTR2AFAAHRARBRARA | |
| SCHEMBL6663942 | 0.84 | HTR2A (0.40) | HSD17B10HTR2AFAAHRARBRARA | |
| SCHEMBL6666748 | 0.84 | HSD17B10 (0.57) | HSD17B10TSHRHTR2AFAAHESR1 | |
| SCHEMBL6662949 | 0.83 | FAAH (0.46) | HSD17B10HTR2AFAAHESR1ADRA2A | |
| SCHEMBL6663171 | 0.82 | SPHK1 (0.34) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0893423-B1 | LIQUID CRYSTAL COMPOUNDS HAVING FLUORINATED LINKAGES, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORP (JP) | 2004-09-01 | — | — | EP | disclosed |