Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 8/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13368743 | 0.90 | MEN1 (0.43) | NTRK1NTRK3ATMKDM4EMEN1 | |
| SCHEMBL13368799 | 0.79 | KDM4E (0.41) | NTRK1NTRK3ATMKDM4EMEN1 | |
| SCHEMBL18969513 | 0.75 | CNR2 (0.45) | NTRK1NTRK3ATMKDM4EMEN1 | |
| SCHEMBL19841330 | 0.74 | RORC (0.41) | ATMKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL23159547 | 0.74 | KDM4E (0.43) | NTRK1NTRK3ATMKDM4EMEN1 | |
| SCHEMBL16293428 | 0.72 | ATM (0.45) | NTRK1NTRK3ATMKDM4EMEN1 | |
| SCHEMBL3757847 | 0.72 | GPR35 (0.48) | NTRK1NTRK3ATMKDM4EMEN1 | |
| SCHEMBL21167461 | 0.71 | NPC1 (0.37) | NTRK1NTRK3ATMKDM4EMEN1 | |
| SCHEMBL19121108 | 0.71 | KDM4E (0.40) | ATMKDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL12726146 | 0.71 | KDM4E (0.45) | NTRK1KDM4EMTNR1APARP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004013139-A2 | PROCESS FOR PREPARING 7-AZAINDOLES | EISAI CO., LTD (JP) | 2004-02-12 | — | — | WO | disclosed |