Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 8/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.46 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | BHMT | Q93088 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322808 | 1.00 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL6447117 | 0.84 | SLC7A5 (0.60) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL4775846 | 0.83 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL6130796 | 0.83 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL4775848 | 0.83 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| D-Leucine SCHEMBL4958590 | 0.83 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| Leucine SCHEMBL6130794 | 0.83 | SLC7A5 (0.78) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL21447999 | 0.83 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL874270 | 0.83 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 | |
| SCHEMBL877833 | 0.83 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446492-A2 | PROCESS FOR THE PREPARATION OF AN ENANTIOMERICALLY ENRICHED A-AMINO ACID | DSM IP Assets B.V. (NL) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003044206-A2 | PROCESS FOR THE PREPARATION OF AN ENANTIOMERICALLY ENRICHED A-AMINO ACID | DSM IP ASSETS B.V. (NL) | 2003-05-30 | — | — | WO | disclosed |