⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35418 | 0.83 | TDP1 (0.31) | — | |
| SCHEMBL30455942 | 0.81 | ATM (0.30) | — | |
| SCHEMBL23644825 | 0.79 | ATM (0.30) | — | |
| SCHEMBL1925622 | 0.79 | — | — | |
| SCHEMBL20544238 | 0.76 | USP2 (0.34) | — | |
| SCHEMBL22788437 | 0.74 | ATM (0.34) | — | |
| SCHEMBL20335453 | 0.73 | TSHR (0.39) | — | |
| SCHEMBL28138681 | 0.70 | HSD17B10 (0.42) | — | |
| SCHEMBL347488 | 0.69 | TSHR (0.35) | — | |
| SCHEMBL650096 | 0.69 | HCAR2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023209631-A1 | METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES | ALCON INC. (CH) | 2023-11-02 | — | — | WO | claimed |
| WO-2023209630-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-02 | — | — | WO | claimed |
| US-20230350100-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-02 | — | — | US | claimed |
| US-8263679-B2 | Prepolymers with dangling polysiloxane-containing polymer chains | NOVARTIS AG (CH) | 2012-09-11 | — | — | US | claimed |
| US-20120046382-A1 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | ALCON INC. (CH) | 2012-02-23 | — | — | US | claimed |
| US-8071658-B2 | Prepolymers with dangling polysiloxane-containing polymer chains | NOVARTIS AG (CH) | 2011-12-06 | — | — | US | claimed |
| JP-2010522265-A | — | — | 2010-07-01 | — | — | JP | claimed |
| EP-2129513-A2 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | Novartis Ag (CH) | 2009-12-09 | — | — | EP | claimed |
| WO-2008116131-A2 | PREPOLYMERS WITH DANGLING POLYSILOXANE-CONTAINING POLYMER CHAINS | NOVARTIS AG (CH) | 2008-09-25 | — | — | WO | claimed |
| US-20080231798-A1 | Prepolymers with dangling polysiloxane-containing polymer chains | ALCON INC. (CH) | 2008-09-25 | — | — | US | claimed |
| EP-1560043-B1 | Soft contact lenses | JOHNSON & JOHNSON VISION CARE (US) | 2008-06-18 | — | — | EP | claimed |
| EP-1560043-A1 | Soft contact lenses | Johnson & Johnson Vision Care, Inc. (US) | 2005-08-03 | — | — | EP | claimed |
| EP-0940693-B1 | Soft contact lenses | JOHNSON & JOHNSON VISION CARE (US) | 2005-06-22 | — | — | EP | claimed |
| US-5998498-A | SILICONE HYDROGEL | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1999-12-07 | — | — | US | claimed |
| EP-0940693-A2 | Soft contact lenses | Johnson & Johnson Vision Products, Inc. (US) | 1999-09-08 | — | — | EP | claimed |
| EP-2926967-B1 | SILICONE HYDROGEL CONTACT LENS HAVING HYDROPHILIC SURFACE | HOYA CORP (JP) | 2025-10-08 | — | — | EP | disclosed |
| US-20250242560-A1 | OPHTHALMIC DEVICES FOR DELIVERY OF HYDROPHOBIC COMFORT AGENTS | ALCON INC (CH) | 2025-07-31 | — | — | US | disclosed |
| WO-2001027174-A1 | SOFT CONTACT LENSES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2001-04-19 | — | — | WO | disclosed |
| US-5998498-A | SILICONE HYDROGEL | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0940693-A2 | Soft contact lenses | Johnson & Johnson Vision Products, Inc. (US) | 1999-09-08 | — | — | EP | disclosed |