SCHEMBL6663645

SCHEMBL6663645

C=CCC(=O)NCCC1CCc2c(OC)ccc3cccc1c23

nearest known ligand 0.80

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 18/20 0.80
MTNR1B P49286 18/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6632982 0.89 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL6633800 0.87 MTNR1B (0.85) MTNR1AMTNR1B
SCHEMBL6633599 0.87 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL6633951 0.85 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL6635495 0.82 MTNR1A (0.75) MTNR1AMTNR1B
SCHEMBL6634055 0.81 MTNR1A (0.78) MTNR1AMTNR1B
SCHEMBL6636026 0.81 MTNR1B (0.74) MTNR1AMTNR1B
SCHEMBL6635804 0.81 MTNR1B (0.74) MTNR1AMTNR1B
SCHEMBL6638835 0.79 MTNR1A (0.71) MTNR1AMTNR1B
SCHEMBL6637041 0.79 MTNR1A (0.81) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1047664-B1 NOVEL TRICYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SERVIER LAB (FR) 2004-05-19 EP disclosed
US-6423870-B1 ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS LES LABORATOIRES SERVIER (FR) 2002-07-23 US disclosed